%0 Journal Article %9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES %A Appenzeller, J. %A Tilvi, S. %A Martin, M. T. %A Gallard, J. F. %A El-bitar, H. %A Dau, E. T. H. %A Debitus, Cécile %A Laurent, Dominique %A Moriou, C. %A Al-Mourabit, A. %T Benzosceptrins A and B with a unique benzocyclobutane skeleton and nagelamide S and T from Pacific sponges %D 2009 %L fdi:010090950 %G ENG %J Organic Letters %@ 1523-7060 %M ISI:000271097100028 %N 21 %P 4874-4877 %R 10.1021/ol901946h %U https://www.documentation.ird.fr/hor/fdi:010090950 %> https://www.documentation.ird.fr/intranet/publi/2024-08/010090950.pdf %V 11 %W Horizon (IRD) %X Four new dimeric pyrrole-2-aminoimidazole alkaloids have been isolated from the Pacific marine sponges Agelas cf. mauritiana and Phakellia sp. They include the unusual C2 symmetrical benzosceptrins A (4) and B (5), which each possess a unique benzocyclobutane skeleton and nagelamides S (6) and T (7). Their structures and relative configuration were elucidated from spectroscopic data. Plausible biogenetic paths for these compounds are also proposed in this paper. %$ 035