@article{fdi:010090642,
  title = {{A}n ecotoxicological view on malaria vector control with ivermectin-treated cattle},
  author = {{H}einrich, {A}. {P}. and {P}ooda, {S}. {H}. and {P}orciani, {A}ng{\'e}lique and {Z}{\'e}la, {L}. and {S}chinzel, {A}. and {M}oiroux, {N}icolas and {R}oberge, {C}. and {M}artina, {M}. {S}. and {C}ourjaud, {A}. {L}. and {D}abir{\'e}, {R}. {K}. and {R}{\¨o}mbke, {J}. and {D}üring, {R}. {A}. and {M}ouline, {K}arine},
  editor = {},
  language = {{ENG}},
  abstract = {{M}alaria remains an enduring challenge in sub-{S}aharan {A}frica, affecting public health and development. {C}ontrol measures can include the use of insecticides that target adult {A}nopheles mosquitoes transmitting the malaria-causing {P}lasmodium parasite. {S}uch mosquitoes can also bite livestock, allowing vector populations to be maintained at levels that enable parasite transmission. {T}hus, one way to control the spread of malaria includes the use of endectocide-treated livestock which renders the blood of cattle toxic to such mosquito populations. {H}ere we present an ecotoxicological perspective on malaria vector control, using cattle treated with the endectocide ivermectin to target zoophagic and opportunistic {A}nopheles coluzzii mosquitoes. {O}ur study employs an innovative, long-acting injectable ivermectin formulation with over 6 months of sustained mosquitocidal activity. {R}obust vector population modelling underscores its promising field effectiveness. {E}nvironmental implications (soil sorption and dissipation) of excreted ivermectin and potential ecotoxicological risks to non-target dung organisms in {W}est {A}frica are discussed, in addition to actionable, locally inspired risk mitigation measures to protect sub-{S}aharan soils and agroecosystems from chemical pollution. {W}e highlight how ecotoxicology and environmental chemistry improve livestock-based vector control with ivermectin for effective and more sustainable malaria management. {M}alaria remains a major public health concern in sub-{S}aharan {A}frica. {T}his study examines the use of a long-acting endectocide formulation given to livestock as a measure to control mosquito vector populations that transmit the malaria-causing parasite in {B}urkina {F}aso.},
  keywords = {},
  booktitle = {},
  journal = {{N}ature {S}ustainability},
  volume = {7},
  numero = {6},
  pages = {724--738},
  ISSN = {2398-9629},
  year = {2024},
  DOI = {10.1038/s41893-024-01332-8},
  URL = {https://www.documentation.ird.fr/hor/fdi:010090642},
}