@article{fdi:010090632,
  title = {{I}nfluence of microbiota on clinical expressions of respiratory viral infections},
  author = {{D}iouf, {F}. {S}. and {A}lou, {M}. {T}. and {M}illion, {M}. and {D}iatta, {G}eorges and {G}oumballa, {N}. and {N}diaye, {D}. and {B}assene, {H}. and {D}ubourg, {G}. and {R}aoult, {D}. and {S}okhna, {C}heikh and {L}agier, {J}. {C}.},
  editor = {},
  language = {{ENG}},
  abstract = {{R}espiratory infections, mainly due to viruses, are among the leading causes of worldwide morbidity andmortality. {W}e investigated the prevalence of viruses and bacteria in a cross-sectional survey conducted in {D}ielmo, a vil-lage in rural {S}enegal with a population of 481 inhabitants. {N}asopharyngeal sampling was performed in 50 symptomaticsubjects and 101 asymptomatic subjects. {S}ymptomatic subjects were defined as individuals presenting with clinicalsigns of respiratory infection, whereas asymptomatic subjects were recruited in the same households. {T}he identificationof pathogens was performed by polymerase chain reaction for 18 respiratory viruses and eight respiratory bacteria.{T}he prevalence results for respiratory viruses detected in each study group demonstrated that 83.6% of symptomatic samples were positive for at least one respiratory virus, and 21.8% were detected in asymptomatic samples. {I}nfluenza {A}({P}50.0001), metapneumovirus ({P}50.04), and enterovirus ({P}50.001) were significantly more prevalent in symptomatic patients. {O}verall, 82.0% of symptomatic subjects and 26.9% of asymptomatic subjects were positive for at least onerespiratory bacterium. {T}he most frequent pathogenic bacteria detected were {M}oraxella catarrhalis (56%) and {S}treptococcus pneumoniae (48.0%) among symptomatic individuals, whereas in asymptomatic subjects {C}orynebacterium propin-quumwas more prevalent (18%). {A} principal component analysis showed that parainfluenzas 2 and 4 were associated with asymptomatic subjects, whereas influenza {A} was associated with the presence of symptoms. {C}onsidering theseresults, a large epidemiological surveillance of the circulation of these respiratory pathogens in the general populationshould be conducted to provide a better understanding of their carriage and to potentially prevent epidemics},
  keywords = {{SENEGAL}},
  booktitle = {},
  journal = {{A}merican {J}ournal of {T}ropical {M}edicine and {H}ygiene},
  volume = {110},
  numero = {2},
  pages = {391--398},
  ISSN = {0002-9637},
  year = {2024},
  DOI = {10.4269/ajtmh.23-0244},
  URL = {https://www.documentation.ird.fr/hor/fdi:010090632},
}