@article{fdi:010090624, title = {{C}ultivable epiphytic bacteria of the {C}hlorophyta {U}lva sp. : diversity, antibacterial, and biofilm-modulating activities}, author = {{P}aulino, {S}. and {P}etek, {S}ylvain and {L}e {S}trat, {Y}. and {B}ourgougnon, {N}. and {L}e {B}lay, {G}.}, editor = {}, language = {{ENG}}, abstract = {{A}ims {M}acroalgae harbor a rich epiphytic microbiota that plays a crucial role in algal morphogenesis and defense mechanisms. {T}his study aims to isolate epiphytic cultivable microbiota from {U}lva sp. surfaces. {V}arious culture media were employed to evaluate a wide range of cultivable microbiota. {O}ur objective was to assess the antibacterial and biofilm-modulating activities of supernatants from isolated bacteria.{M}ethods and results {S}ixty-nine bacterial isolates from {U}lva sp. were identified based on 16{S} r{RNA} gene sequencing. {T}heir antibacterial activity and biofilm modulation potential were screened against three target marine bacteria: 45%, mostly affiliated with {G}ammaproteobacteria and mainly grown on diluted {R}2{A} medium ({R}2{A}d), showed strong antibacterial activity, while 18% had a significant impact on biofilm modulation. {M}olecular network analysis was carried out on four bioactive bacterial supernatants, revealing new molecules potentially responsible for their activities.{C}onclusion {R}2{A}d offered the greatest diversity and proportion of active isolates. {T}he molecular network approach holds promise for both identifying bacterial isolates based on their molecular production and characterizing antibacterial and biofilm-modulating activities.}, keywords = {{U}lva sp ; epiphytic bacteria ; antibacterial activity ; biofilm assays ; cultivable microbiota ; molecular network analysis}, booktitle = {}, journal = {{J}ournal of {A}pplied {M}icrobiology}, volume = {135}, numero = {5}, pages = {lxae099 [16 p.]}, ISSN = {1364-5072}, year = {2024}, DOI = {10.1093/jambio/lxae099}, URL = {https://www.documentation.ird.fr/hor/fdi:010090624}, }