%0 Journal Article
%9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES
%A Marchio, A.
%A Sitbounlang, P.
%A Deharo, Eric
%A Paboriboune, P.
%A Pineau, P.
%T Concealed for a long time on the marches of empires : hepatitis B virus genotype I
%D 2023
%L fdi:010090347
%G ENG
%J Microorganisms
%K Hepadnaviridae ; HBV ; genotype I ; recombinant ; ethnic minorities ; Southeast Asian Massif ; Zomia ; Guangxi
%K CHINE ; LAOS ; THAILANDE ; VIET NAM ; INDE
%M ISI:001079670700001
%N 9
%P 2204 [18 ]
%R 10.3390/microorganisms11092204
%U https://www.documentation.ird.fr/hor/fdi:010090347
%> https://horizon.documentation.ird.fr/exl-doc/pleins_textes/2023-11/010090347.pdf
%V 11
%W Horizon (IRD)
%X Genotype I, the penultimate HBV genotype to date, was granted the status of a bona fide genotype only in the XXIst century after some hesitations. The reason for these hesitations was that genotype I is a complex recombinant virus formed with segments from three original genotypes, A, C, and G. It was estimated that genotype I is responsible for only an infinitesimal fraction (<1.0%) of the chronic HBV infection burden worldwide. Furthermore, most probably due to its recent discovery and rarity, the natural history of infection with genotype I is poorly known in comparison with those of genotypes B or C that predominate in their area of circulation. Overall, genotype I is a minor genotype infecting ethnic minorities. It is endemic to the Southeast Asian Massif or Eastern Zomia, a vast mountainous or hilly region of 2.5 million km(2) spreading from Eastern India to China, inhabited by a little more than 100 million persons belonging primarily to ethnic minorities speaking various types of languages (Tibeto-Burman, Austroasiatic, and Tai-Kadai) who managed to escape the authority of central states during historical times. Genotype I consists of two subtypes: I1, present in China, Laos, Thailand, and Vietnam; and I2, encountered in India, Laos, and Vietnam.
%$ 052 ; 020