@article{fdi:010090347, title = {{C}oncealed for a long time on the marches of empires : hepatitis {B} virus genotype {I}}, author = {{M}archio, {A}. and {S}itbounlang, {P}. and {D}eharo, {E}ric and {P}aboriboune, {P}. and {P}ineau, {P}.}, editor = {}, language = {{ENG}}, abstract = {{G}enotype {I}, the penultimate {HBV} genotype to date, was granted the status of a bona fide genotype only in the {XXI}st century after some hesitations. {T}he reason for these hesitations was that genotype {I} is a complex recombinant virus formed with segments from three original genotypes, {A}, {C}, and {G}. {I}t was estimated that genotype {I} is responsible for only an infinitesimal fraction (<1.0%) of the chronic {HBV} infection burden worldwide. {F}urthermore, most probably due to its recent discovery and rarity, the natural history of infection with genotype {I} is poorly known in comparison with those of genotypes {B} or {C} that predominate in their area of circulation. {O}verall, genotype {I} is a minor genotype infecting ethnic minorities. {I}t is endemic to the {S}outheast {A}sian {M}assif or {E}astern {Z}omia, a vast mountainous or hilly region of 2.5 million km(2) spreading from {E}astern {I}ndia to {C}hina, inhabited by a little more than 100 million persons belonging primarily to ethnic minorities speaking various types of languages ({T}ibeto-{B}urman, {A}ustroasiatic, and {T}ai-{K}adai) who managed to escape the authority of central states during historical times. {G}enotype {I} consists of two subtypes: {I}1, present in {C}hina, {L}aos, {T}hailand, and {V}ietnam; and {I}2, encountered in {I}ndia, {L}aos, and {V}ietnam.}, keywords = {{H}epadnaviridae ; {HBV} ; genotype {I} ; recombinant ; ethnic minorities ; {S}outheast {A}sian {M}assif ; {Z}omia ; {G}uangxi ; {CHINE} ; {LAOS} ; {THAILANDE} ; {VIET} {NAM} ; {INDE}}, booktitle = {}, journal = {{M}icroorganisms}, volume = {11}, numero = {9}, pages = {2204 [18 ]}, year = {2023}, DOI = {10.3390/microorganisms11092204}, URL = {https://www.documentation.ird.fr/hor/fdi:010090347}, }