@article{fdi:010090190, title = {{SARS}-{C}o{V}-2 seroprevalence and living conditions in {B}amako ({M}ali) : a cross-sectional multistage household survey after the first epidemic wave, 2020}, author = {{C}issoko, {M}. and {L}andier, {J}ordi and {K}ouriba, {B}. and {S}angare, {A}. {K}. and {K}atile, {A}. and {D}jimde, {A}. {A}. and {B}erthe, {I}. and {T}raore, {S}. and {T}hera, {I}. and {H}adiata, {M}. and {S}ogodogo, {E}. and {C}oulibaly, {K}. and {G}uindo, {A}bdoulaye and {D}embele, {O}. and {S}anogo, {S}. and {D}oumbia, {Z}. and {D}ara, {C}. and {A}ltmann, {M}. and {B}onnet, {E}mmanuel and {B}alique, {H}. and {S}agaon {T}eyssier, {L}uis and {V}idal, {L}aurent and {S}agara, {I}. and {B}endiane, {M}. {K}. and {G}audart, {J}.}, editor = {}, language = {{ENG}}, abstract = {{O}bjectives {I}n low-income settings with limited access to diagnosis, {COVID}-19 information is scarce. {I}n {S}eptember 2020, after the first {COVID}-19 wave, {M}ali reported 3086 confirmed cases and 130 deaths. {M}ost reports originated from {B}amako, with 1532 cases and 81 deaths (2.42 million inhabitants). {T}his observed prevalence of 0.06% appeared very low. {O}ur objective was to estimate {SARS}-{C}o{V}-2 infection among inhabitants of {B}amako, after the first epidemic wave. {W}e assessed demographic, social and living conditions, health behaviours and knowledges associated with {SARS}-{C}o{V}-2 seropositivity. {S}ettings {W}e conducted a cross-sectional multistage household survey during {S}eptember 2020, in three neighbourhoods of the commune {VI} ({B}amako), where 30% of the cases were reported. {P}articipants {W}e recruited 1526 inhabitants in 3 areas, that is, 306 households, and 1327 serological results (>= 1 years), 220 household questionnaires and collected answers for 962 participants (>= 12 years). {P}rimary and secondary outcome measures {W}e measured serological status, detecting {SARS}-{C}o{V}-2 spike protein antibodies in blood sampled. {W}e documented housing conditions and individual health behaviours through questionnaires among participants. {W}e estimated the number of {SARS}-{C}o{V}-2 infections and deaths in the population of {B}amako using the age and sex distributions. {R}esults {T}he prevalence of {SARS}-{C}o{V}-2 seropositivity was 16.4% (95% {CI} 15.1% to 19.1%) after adjusting on the population structure. {T}his suggested that similar to 400 000 cases and similar to 2000 deaths could have occurred of which only 0.4% of cases and 5% of deaths were officially reported. {Q}uestionnaires analyses suggested strong agreement with washing hands but lower acceptability of movement restrictions (lockdown/curfew), and mask wearing. {C}onclusions {T}he first wave of {SARS}-{C}o{V}- 2 spread broadly in {B}amako. {E}xpected fatalities remained limited largely due to the population age structure and the low prevalence of comorbidities. {I}mproving diagnostic capacities to encourage testing and preventive behaviours, and avoiding the spread of false information remain key pillars, regardless of the developed or developing setting. {E}thics {T}his study was registered in the registry of the ethics committee of the {F}aculty of {M}edicine and {O}donto-{S}tomatology and the {F}aculty of {P}harmacy, {B}amako, {M}ali, under the number: 2020/162/{CA}/{FMOS}/{FAPH}.}, keywords = {{COVID}-19 ; {EPIDEMIOLOGY} ; {T}ropical medicine ; {MALI} ; {BAMAKO}}, booktitle = {}, journal = {{BMJ} {O}pen}, volume = {13}, numero = {4}, pages = {e067124 [12 p.]}, ISSN = {2044-6055}, year = {2023}, DOI = {10.1136/bmjopen-2022-067124}, URL = {https://www.documentation.ird.fr/hor/fdi:010090190}, }