@article{fdi:010090101,
  title = {{P}rediction of crossover recombination using parental genomes},
  author = {{P}enuela, {M}. and {R}iccio-{R}engifo, {C}. and {F}inke, {J}. and {R}ocha, {C}. and {G}kanogiannis, {A}. and {W}ing, {R}. {A}. and {L}orieux, {M}athias},
  editor = {},
  language = {{ENG}},
  abstract = {{M}eiotic recombination is a crucial cellular process, being one of the major drivers of evolution and adaptation of species. {I}n plant breeding, crossing is used to introduce genetic variation among individuals and populations. {W}hile different approaches to predict recombination rates for different species have been developed, they fail to estimate the outcome of crossings between two specific accessions. {T}his paper builds on the hypothesis that chromosomal recombination correlates positively to a measure of sequence identity. {I}t presents a model that uses sequence identity, combined with other features derived from a genome alignment (including the number of variants, inversions, absent bases, and {C}ent{O} sequences) to predict local chromosomal recombination in rice. {M}odel performance is validated in an inter-subspecific indica x japonica cross, using 212 recombinant inbred lines. {A}cross chromosomes, an average correlation of about 0.8 between experimental and prediction rates is achieved. {T}he proposed model, a characterization of the variation of the recombination rates along the chromosomes, can enable breeding programs to increase the chances of creating novel allele combinations and, more generally, to introduce new varieties with a collection of desirable traits. {I}t can be part of a modern panel of tools that breeders can use to reduce costs and execution times of crossing experiments.},
  keywords = {},
  booktitle = {},
  journal = {{PL}o{S} {O}ne},
  volume = {18},
  numero = {2},
  pages = {e0281804 [21 p.]},
  ISSN = {1932-6203},
  year = {2023},
  DOI = {10.1371/journal.pone.0281804},
  URL = {https://www.documentation.ird.fr/hor/fdi:010090101},
}