@article{fdi:010090054,
  title = {{I}nvestigation of a mpox outbreak in {C}entral {A}frican {R}epublic, 2021-2022},
  author = {{B}esombes, {C}. and {M}brenga, {F}. and {M}alaka, {C}. and {G}onofio, {E}. and {S}chaeffer, {L}. and {K}onamna, {X}. and {S}elekon, {B}. and {N}amsenei-{D}ankpea, {J}. and {L}emon, {C}. {G}. and {L}andier, {J}ordi and von {P}laten, {C}. and {G}essain, {A}. and {M}anuguerra, {J}. {C}. and {F}ontanet, {A}. and {N}akoun{\'e}, {E}.},
  editor = {},
  language = {{ENG}},
  abstract = {{H}uman monkeypox virus is spreading globally, and more information is required about its epidemiological and clinical disease characteristics in endemic countries. {W}e report the investigation of an outbreak in {N}ovember 2021 in {C}entral {A}frican {R}epublic ({CAR}). {T}he primary case, a hunter, fell ill after contact with a non-human primate at the frontier between forest and savannah. {T}he ensuing investigation in a small nearby town concerned two families and four waves of inter-human transmission, with 14 confirmed cases, 11 suspected cases and 17 non-infected contacts, and a secondary attack rate of 59.5% (25/42). {C}omplications were observed in 12 of the 19 (63.2%) confirmed and suspected cases with available clinical follow-up data: eight cases of bronchopneumonia, two of severe dehydration, one corneal ulcer, one abscess, two cutaneous superinfections, and six cutaneous sequelae (cheloid scars, or depigmentation). {T}here was one death, giving a case fatality ratio of 1/25 (4.0%) for confirmed and suspected cases. {T}his outbreak, with the largest number of confirmed cases ever described in {CAR}, confirms the potential severity of the disease associated with clade {I} monkeypox viruses, and highlights the need for rapid control over virus circulation to prevent the further national and international spread of infection.},
  keywords = {mpox ; {M}onkeypox virus ; {C}entral {A}frican {R}epublic ; {S}urveillance ; {O}utbreak ; investigation ; {Z}oonosis ; {E}merging infectious diseases ; {CENTRAFRIQUE}},
  booktitle = {},
  journal = {{O}ne {H}ealth},
  volume = {16},
  numero = {},
  pages = {100523 [9 p.]},
  year = {2023},
  DOI = {10.1016/j.onehlt.2023.100523},
  URL = {https://www.documentation.ird.fr/hor/fdi:010090054},
}