Caudal F. auteur aut IRD Rodrigues S. auteur aut IRD Dufour A. auteur aut IRD Artigaud S. auteur aut IRD Le Blay G. auteur aut IRD Petek Sylvain auteur aut IRD Bazire A. auteur aut IRD text journalArticle eng text/pdf reformatted digital access Pathogenic bacteria and their biofilms are involved in many human and animal diseases and are a major public health problem with, among other things, the development of antibiotic resistance. These biofilms are known to induce chronic infections for which classical treatments using antibiotic therapy are often ineffective. Sponges are sessile filter-feeding marine organisms known for their dynamic symbiotic partnerships with diverse microorganisms and their production of numerous metabolites of interest. In this study, we investigated the antibiofilm efficacy of different extracts from sponges, isolated in Wallis, without biocidal activity. Out of the 47 tested extracts, from 28 different genera, 11 showed a strong activity against Vibrio harveyi biofilm formation. Moreover, one of these extracts also inhibited two quorum-sensing pathways of V. harveyi. specialized biofilm Vibrio harveyi sponge extract anti-biofilm activity marine natural products 035 084 11 7 1762 [15 p.] 2023 https://www.documentation.ird.fr/hor/fdi:010090048 10.3390/microorganisms11071762 [F B010090048] https://www.documentation.ird.fr/hor/fdi:010090048 https://horizon.documentation.ird.fr/exl-doc/pleins_textes/2023-09/010090048.pdf IRD - Base Horizon / Pleins textes 2023-09-22 2025-02-24 fdi:010090048 fre