@article{fdi:010090048, title = {{E}xtracts from {W}allis sponges inhibit vibrio harveyi biofilm formation}, author = {{C}audal, {F}. and {R}odrigues, {S}. and {D}ufour, {A}. and {A}rtigaud, {S}. and {L}e {B}lay, {G}. and {P}etek, {S}ylvain and {B}azire, {A}.}, editor = {}, language = {{ENG}}, abstract = {{P}athogenic bacteria and their biofilms are involved in many human and animal diseases and are a major public health problem with, among other things, the development of antibiotic resistance. {T}hese biofilms are known to induce chronic infections for which classical treatments using antibiotic therapy are often ineffective. {S}ponges are sessile filter-feeding marine organisms known for their dynamic symbiotic partnerships with diverse microorganisms and their production of numerous metabolites of interest. {I}n this study, we investigated the antibiofilm efficacy of different extracts from sponges, isolated in {W}allis, without biocidal activity. {O}ut of the 47 tested extracts, from 28 different genera, 11 showed a strong activity against {V}ibrio harveyi biofilm formation. {M}oreover, one of these extracts also inhibited two quorum-sensing pathways of {V}. harveyi.}, keywords = {biofilm ; {V}ibrio harveyi ; sponge extract ; anti-biofilm activity ; marine ; natural products}, booktitle = {}, journal = {{M}icroorganisms}, volume = {11}, numero = {7}, pages = {1762 [15 p.]}, year = {2023}, DOI = {10.3390/microorganisms11071762}, URL = {https://www.documentation.ird.fr/hor/fdi:010090048}, }