@article{fdi:010089751,
  title = {{A}symptomatic {L}eishmania infantum infection in dogs and dog owners in an endemic area in southeast {F}rance},
  author = {{H}ide, {M}. and {M}ichel, {G}. and {L}egueult, {K}. and {P}in, {R}. and {L}eonard, {S}. and {S}imon, {L}. and {B}anuls, {A}nne-{L}aure and {D}elaunay, {P}. and {M}arty, {P}. and {P}omares, {C}.},
  editor = {},
  language = {{ENG}},
  abstract = {{T}he prevalence of asymptomatic leishmaniasis in dogs and their owners in the main endemic areas of {F}rance has not been studied to date. {T}he objective of this study was to quantify asymptomatic {L}eishmania infantum infection in southeast {F}rance in healthy people and their dogs using molecular and serological screening techniques. {W}e examined the presence of parasitic {DNA} using specific {PCR} targeting kinetoplast {DNA} (k{DNA}) and specific antibodies by serology ({ELISA} for dogs and {W}estern blot for humans) among immunocompetent residents and their dogs in the {A}lpes-{M}aritimes. {R}esults from 343 humans and 607 dogs were included. 46.9% (n = 161/343) of humans and 18.3% (n = 111/607) of dogs were {PCR} positive; 40.2% of humans (n = 138/343) and 9.9% of dogs (n = 60/607) were serology positive. {A}ltogether, 66.2% of humans (n = 227) and 25.7% of dogs (n = 156) had positive serologies and/or positive {PCR} test results. {S}hort-haired dogs were more frequently infected (71.8%, n = 112) than long-haired dogs (12.2%, n = 19) (p = 0.043). {D}ogs seemed to be more susceptible to asymptomatic infection according to their breed types (higher infection rates in scenthounds, gun dogs and herding dogs) (p = 0.04). {T}he highest proportion of dogs and human asymptomatic infections was found in the {V}ence {R}egion, corresponding to 28.2% (n = 20/71) of dogs and 70.5% (n = 31/44) of humans (4.5/100,000 people). {I}n conclusion, the percentage of infections in asymptomatic humans is higher than in asymptomatic dogs in the studied endemic area. {I}t is questionable whether asymptomatic infection in humans constitutes a risk factor for dogs.},
  keywords = {{A}symptomatic {L}eishmania infection ; {H}umans ; {D}ogs ; k{DNA} {PCR} ; {ELISA} ; {W}estern {B}lot ; {FRANCE}},
  booktitle = {},
  journal = {{P}arasite},
  volume = {31},
  numero = {},
  pages = {16 [9 ]},
  ISSN = {1252-607{X}},
  year = {2024},
  DOI = {10.1051/parasite/2024019},
  URL = {https://www.documentation.ird.fr/hor/fdi:010089751},
}