@article{fdi:010089651,
  title = {{P}angolin genomes offer key insights and resources for the {W}orld's most trafficked wild mammals},
  author = {{H}eighton, {S}. {P}. and {A}llio, {R}. and {M}urienne, {J}. and {S}almona, {J}ordi and {M}eng, {H}. and {S}cornavacca, {C}. and {B}astos, {A}. {D}. {S}. and {N}jiokou, {F}. and {P}ietersen, {D}. {W}. and {T}ilak, {M}. {K}. and {L}uo, {S}. {J}. and {D}elsuc, {F}. and {G}aubert, {P}hilippe},
  editor = {},
  language = {{ENG}},
  abstract = {{P}angolins form a group of scaly mammals that are trafficked at record numbers for their meat and purported medicinal properties. {D}espite their conservation concern, knowledge of their evolution is limited by a paucity of genomic data. {W}e aim to produce exhaustive genomic resources that include 3,238 orthologous genes and whole-genome polymorphisms to assess the evolution of all eight extant pangolin species. {R}obust orthologous gene-based phylogenies recovered the monophyly of the three genera and highlighted the existence of an undescribed species closely related to {S}outheast {A}sian pangolins. {S}ignatures of middle {M}iocene admixture between an extinct, possibly {E}uropean, lineage and the ancestor of {S}outheast {A}sian pangolins, provide new insights into the early evolutionary history of the group. {D}emographic trajectories and genome-wide heterozygosity estimates revealed contrasts between continental versus island populations and species lineages, suggesting that conservation planning should consider intraspecific patterns. {W}ith the expected loss of genomic diversity from recent, extensive trafficking not yet realized in pangolins, we recommend that populations be genetically surveyed to anticipate any deleterious impact of the illegal trade. {F}inally, we produce a complete set of genomic resources that will be integral for future conservation management and forensic endeavors for pangolins, including tracing their illegal trade. {T}hese comprise the completion of whole-genomes for pangolins through the hybrid assembly of the first reference genome for the giant pangolin ({S}mutsia gigantea) and new draft genomes (similar to 43x-77x) for four additional species, as well as a database of orthologous genes with over 3.4 million polymorphic sites.},
  keywords = {pholidota ; full genomes ; genomic diversity ; conservation ; ancient ; admixture ; novel taxon},
  booktitle = {},
  journal = {{M}olecular {B}iology and {E}volution},
  volume = {40},
  numero = {10},
  pages = {msad190 [18 p.]},
  ISSN = {0737-4038},
  year = {2023},
  DOI = {10.1093/molbev/msad190},
  URL = {https://www.documentation.ird.fr/hor/fdi:010089651},
}