%0 Journal Article
%9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES
%A Montemurro, N.
%A Manasfi, R.
%A Chiron, Serge
%A Perez, S.
%T Evaluation of different QuEChERS-based methods for the extraction of 48 wastewater-derived organic contaminants from soil and lettuce root using high-resolution LC-QTOF with MRMHR and SWATH acquisition modes
%D 2024
%L fdi:010089643
%G ENG
%J Environmental Science and Pollution Research
%@ 0944-1344
%K Pharmaceuticals ; Wastewater reuse ; Soil contamination ; Root uptake ; Modified QuEChERS ; LC-HRMS/MS
%M ISI:001165179900013
%N 13
%P 20084-20092
%R 10.1007/s11356-024-32423-w
%U https://www.documentation.ird.fr/hor/fdi:010089643
%> https://horizon.documentation.ird.fr/exl-doc/pleins_textes/2024-04/010089643.pdf
%V 31
%W Horizon (IRD)
%X The reuse of treated wastewater in agriculture is an important route of introducing a large number of organic contaminants into the agroecosystem. In this study, a modified QuEChERS-based approach was developed for rapid, simple, and simultaneous extraction of 48 organic wastewater-derived contaminants from soil and lettuce root. Twenty-two different (modification) scenarios of the known (or original) QuEChERS method have been tested, in order to obtain best and well-compromised recoveries for all target compounds for soil and roots. Finally, a common method was chosen for both matrices consisting of a single extraction step using EDTA-Mcllvaine buffer and the unbuffered Original QuEChERS salts. Method performance was accomplished by liquid chromatography coupled with high-resolution mass spectrometry on a QToF-MS system using two different acquisition modes, the ultra-fast high-resolution multiple reaction monitoring (MRMHR) mode and the innovative Sequential Window Acquisition of All Theoretical Fragment-Ion (SWATH) mode. Performance characterization was evaluated in terms of recovery, linearity, intra-day precision, method detection limits (MDLs), method quantification limits (MQLs), and matrix effect (ME). Recoveries in MRMHR mode ranged from 63 to 111% and 54 to 104% for lettuce root and soil, respectively, for most of compounds in MRMHR mode and from 56 to 121% and 54 to 104% for lettuce root and soil, respectively, for most of compounds in SWATH. Whereas, MQLs ranged from 0.03 to 0.92 ng g(-1) in MRMHR and from 0.03 to 82 ng g(-1) in SWATH for lettuce root, and from 0.02 to 0.44 ng g(-1) in MRMHR and 0.02 to 0.14 ng g(-1) in SWATH for soil. The method was then applied to follow the target compounds in soil and lettuce root, where the system lettuce-soil was irrigated with treated wastewater under real greenhouse conditions. Five and 17 compounds were detected in lettuce root and soil, respectively.
%$ 038 ; 020 ; 068