@article{fdi:010089643,
  title = {{E}valuation of different {Q}u{EC}h{ERS}-based methods for the extraction of 48 wastewater-derived organic contaminants from soil and lettuce root using high-resolution {LC}-{QTOF} with {MRMHR} and {SWATH} acquisition modes},
  author = {{M}ontemurro, {N}. and {M}anasfi, {R}. and {C}hiron, {S}erge and {P}erez, {S}.},
  editor = {},
  language = {{ENG}},
  abstract = {{T}he reuse of treated wastewater in agriculture is an important route of introducing a large number of organic contaminants into the agroecosystem. {I}n this study, a modified {Q}u{EC}h{ERS}-based approach was developed for rapid, simple, and simultaneous extraction of 48 organic wastewater-derived contaminants from soil and lettuce root. {T}wenty-two different (modification) scenarios of the known (or original) {Q}u{EC}h{ERS} method have been tested, in order to obtain best and well-compromised recoveries for all target compounds for soil and roots. {F}inally, a common method was chosen for both matrices consisting of a single extraction step using {EDTA}-{M}cllvaine buffer and the unbuffered {O}riginal {Q}u{EC}h{ERS} salts. {M}ethod performance was accomplished by liquid chromatography coupled with high-resolution mass spectrometry on a {QT}o{F}-{MS} system using two different acquisition modes, the ultra-fast high-resolution multiple reaction monitoring ({MRMHR}) mode and the innovative {S}equential {W}indow {A}cquisition of {A}ll {T}heoretical {F}ragment-{I}on ({SWATH}) mode. {P}erformance characterization was evaluated in terms of recovery, linearity, intra-day precision, method detection limits ({MDL}s), method quantification limits ({MQL}s), and matrix effect ({ME}). {R}ecoveries in {MRMHR} mode ranged from 63 to 111% and 54 to 104% for lettuce root and soil, respectively, for most of compounds in {MRMHR} mode and from 56 to 121% and 54 to 104% for lettuce root and soil, respectively, for most of compounds in {SWATH}. {W}hereas, {MQL}s ranged from 0.03 to 0.92 ng g(-1) in {MRMHR} and from 0.03 to 82 ng g(-1) in {SWATH} for lettuce root, and from 0.02 to 0.44 ng g(-1) in {MRMHR} and 0.02 to 0.14 ng g(-1) in {SWATH} for soil. {T}he method was then applied to follow the target compounds in soil and lettuce root, where the system lettuce-soil was irrigated with treated wastewater under real greenhouse conditions. {F}ive and 17 compounds were detected in lettuce root and soil, respectively.},
  keywords = {{P}harmaceuticals ; {W}astewater reuse ; {S}oil contamination ; {R}oot uptake ; {M}odified {Q}u{EC}h{ERS} ; {LC}-{HRMS}/{MS}},
  booktitle = {},
  journal = {{E}nvironmental {S}cience and {P}ollution {R}esearch},
  volume = {31},
  numero = {13},
  pages = {20084--20092},
  ISSN = {0944-1344},
  year = {2024},
  DOI = {10.1007/s11356-024-32423-w},
  URL = {https://www.documentation.ird.fr/hor/fdi:010089643},
}