@article{fdi:010089625, title = {{B}iological effects of {L}ippia alba essential oil against {A}nopheles gambiae and {A}edes aegypti}, author = {{C}oulibaly, {F}. {H}. and {R}ossignol, {M}arie and {H}addad, {M}ohamed and {C}arrasco, {D}avid and {A}zokou, {A}. and {V}alente, {A}deline and {G}inibre, {C}arole and {K}one, {M}. {W}. and {C}handre, {F}abrice}, editor = {}, language = {{ENG}}, abstract = {{T}he management of mosquito resistance to chemical insecticides and the biting behaviour of some species are motivating the search for complementary and/or alternative control methods. {T}he use of plants is increasingly considered as a sustainable biological solution for vector control. {T}he aim of this study was to evaluate the biological effects of the essential oil ({EO}) of {L}ippia alba harvested in {A}bidjan ({C}ote d'{I}voire) against {A}nopheles gambiae and {A}edes aegypti mosquitoes. {P}hytochemical compounds were identified by {GC}-{MS}. {K}nockdown and mortality were determined according to the {WHO} test tube protocol. {C}ontact irritancy was assessed by observing the movement of mosquitoes from a treated {WHO} tube to a second untreated tube. {N}on-contact repellency was assessed using a standardised high-throughput screening system ({HITSS}). {B}lood meal inhibition was assessed using a membrane feeding assay treated with {EO}. {T}he {EO} was identified as the citral chemotype. {T}he {EO} gave 100% {KD}60 in both species at a concentration of 1%. {M}ortalities of 100% were recorded with {A}n. gambiae and {A}e. aegypti at concentrations of 1% and 5% respectively. {T}he highest proportions of females escaping during the contact irritancy test were 100% for {A}n. gambiae at 1% concentration and 94% for {A}e. aegypti at 2.5% concentration. {T}he 1% concentration produced the highest proportions of repelled mosquitoes in the non-contact repellency tests: 76.8% ({A}n. gambiae) and 68.5% ({A}e. aegypti). {T}he blood meal inhibition rate at a dose of 10% was 98.4% in {A}e. aegypti but only 15.5% in {A}n. gambiae. {T}he citral chemotype of {L}. alba {EO} has promising biological effects in both species that make it a potentially good candidate for its use in mosquito control. {T}he results obtained in this study encourage the further evaluation of {L}. alba {EO}s from other localities and of different chemotypes, under laboratory and field conditions.}, keywords = {{COTE} {D}'{IVOIRE}}, booktitle = {}, journal = {{S}cientific {R}eports - {N}ature}, volume = {14}, numero = {1}, pages = {3508 [12 ]}, ISSN = {2045-2322}, year = {2024}, DOI = {10.1038/s41598-024-52801-1}, URL = {https://www.documentation.ird.fr/hor/fdi:010089625}, }