@article{fdi:010089021,
  title = {{A}rm {B}ased on {LE}g blood pressures ({ABLE}-{BP}) : can systolic leg blood pressure measurements predict systolic brachial blood pressure ? : protocol for an individual participant data meta-analysis from the {INTERPRESS}-{IPD} {C}ollaboration},
  author = {{M}c{D}onagh, {S}.{T}.{J}. and {S}heppard, {J}.{P}. and {W}arren, {F}.{C}. and {B}oddy, {K}. and {F}armer, {L}. and {S}hore, {H}. and {W}illiams, {P}. and {L}ewis, {P}.{S}. and {B}aumber, {R}. and {F}ordham, {J}. and {M}artin, {U}. and {A}boyans, {V}. and {C}lark, {C}.{E}. and {W}hite, {J}. and {F}errucci, {L}. and {E}rbel, {R}. and {W}esterink, {J}. and {C}riqui, {M}. and {L}ahoz, {C}. and {G}uerchet, {M}a{\¨e}lenn and {A}llison, {M}. and {M}c{D}ermott, {M}. and {E}speland, {M}. and {D}ahl, {M}. and {S}hore, {A}. and {B}lanes, {R}.{R}.},
  editor = {},
  language = {{ENG}},
  abstract = {{I}ntroduction {B}lood pressure ({BP}) is normally measured on the upper arm, and guidelines for the diagnosis and treatment of high {BP} are based on such measurements. {L}eg {BP} measurement can be an alternative when brachial {BP} measurement is impractical, due to injury or disability. {L}imited data exist to guide interpretation of leg {BP} values for hypertension management; study-level systematic review findings suggest that systolic {BP} ({SBP}) is 17 mm {H}g higher in the leg than the arm. {H}owever, uncertainty remains about the applicability of this figure in clinical practice due to substantial heterogeneity. {A}ims {T}o examine the relationship between arm and leg {SBP}, develop and validate a multivariable model predicting arm {SBP} from leg {SBP} and investigate the prognostic association between leg {SBP} and cardiovascular disease and mortality. {M}ethods and analysis {I}ndividual participant data ({IPD}) meta-analyses using arm and leg {SBP} measurements for 33 710 individuals from 14 studies within the {I}nter-arm blood pressure difference {IPD} ({INTERPRESS}-{IPD}) {C}ollaboration. {W}e will explore cross-sectional relationships between arm and leg {SBP} using hierarchical linear regression with participants nested by study, in multivariable models. {P}rognostic models will be derived for all-cause and cardiovascular mortality and cardiovascular events. {E}thics and dissemination {D}ata originate from studies with prior ethical approval and consent, and data sharing agreements are in place?no further approvals are required to undertake the secondary analyses proposed in this protocol. {F}indings will be published in peer- reviewed journal articles and presented at conferences. {A} comprehensive dissemination strategy is in place, integrated with patient and public involvement.},
  keywords = {{EUROPE} ; {ETATS} {UNIS} ; {AFRIQUE}},
  booktitle = {},
  journal = {{BMJ} {O}pen},
  volume = {11},
  numero = {3},
  pages = {e040481 [10 ]},
  ISSN = {2044-6055},
  year = {2021},
  DOI = {10.1136/bmjopen-2020-040481},
  URL = {https://www.documentation.ird.fr/hor/fdi:010089021},
}