@article{fdi:010088719, title = {{L}imited association between {W}olbachia and {P}lasmodium falciparum infections in natural populations of the major malaria mosquito {A}nopheles moucheti}, author = {{M}ouillaud, {T}h{\'e}o and {B}erger, {A}udric and {B}uysse, {M}. and {R}ahola, {N}il and {D}aron, {J}. and {A}gbor, {J}. {P}. and {S}ango, {S}. {N}. and {N}eafsey, {D}. {E}. and {D}uron, {O}. and {A}yala, {D}iego}, editor = {}, language = {{ENG}}, abstract = {{S}ince the discovery of natural malaria vector populations infected by the endosymbiont bacterium {W}olbachia, a renewed interest has arisen for using this bacterium as an alternative for malaria control. {A}mong naturally infected mosquitoes, {A}nopheles moucheti, a major malaria mosquito in {C}entral {A}frica, exhibits one of the highest prevalences of {W}olbachia infection. {T}o better understand whether this maternally inherited bacterium could be used for malaria control, we investigated {W}olbachia influence in {A}n. moucheti populations naturally infected by the malaria parasite {P}lasmodium falciparum. {T}o this end, we collected mosquitoes in a village from {C}ameroon, {C}entral {A}frica, where this mosquito is the main malaria vector. {W}e found that the prevalence of {W}olbachia bacterium was almost fixed in the studied mosquito population, and was higher than previously recorded. {W}e also quantified {W}olbachia in whole mosquitoes and dissected abdomens, confirming that the bacterium is also elsewhere than in the abdomen, but at lower density. {F}inally, we analyzed the association of {W}olbachia presence and density on {P}. falciparum infection. {W}olbachia density was slightly higher in mosquitoes infected with the malaria parasite than in uninfected mosquitoes. {H}owever, we observed no correlation between the {P}. falciparum and {W}olbachia densities. {I}n conclusion, our study indicates that naturally occurring {W}olbachia infection is not associated to {P}. falciparum development within {A}n. moucheti mosquitoes.}, keywords = {{A}nopheles moucheti ; malaria control ; {P}lasmodium infection ; {W}olbachia ; {CAMEROUN}}, booktitle = {}, journal = {{E}volutionary {A}pplications}, volume = {16}, numero = {}, pages = {1999--2006}, ISSN = {1752-4571}, year = {2023}, DOI = {10.1111/eva.13619}, URL = {https://www.documentation.ird.fr/hor/fdi:010088719}, }