@article{fdi:010088578,
  title = {{M}odelling spatiotemporal distributions of {V}ulcanodinium rugosum and pinnatoxin {G} in {F}rench {M}editerranean lagoons : application to human health risk characterisation},
  author = {{B}ouquet, {A}. and {T}h{\'e}bault, {A}. and {A}rnich, {N}. and {F}oucault, {E}. and {C}aillard, {E}. and {G}ianaroli, {C}. and {B}ellamy, {E}. and {R}olland, {J}. {L}. and {L}aabir, {M}ohamed and {A}badie, {E}.},
  editor = {},
  language = {{ENG}},
  abstract = {{C}onsumption of seafood contaminated by phycotoxins produced by harmful algae is a major issue in human public health. {H}armful algal blooms are driven by a multitude of environmental variables; therefore predicting human dietary exposure to phycotoxins based on these variables is a promising approach in health risk management. {I}n this study, we attempted to predict the human health risks associated with {V}ulcanodinium rugosum and its neurotoxins, pinnatoxins ({P}n{TX}s), which have been regularly found in {M}editerranean lagoons since their identification in 2011. {B}ased on environmental variables collected over 1 year in four {M}editerranean lagoons, we developed linear mixed models to predict the presence of {V}. rugosum and {P}n{TX} {G} contamination of mussels. {W}e found that the occurrence of {V}. rugosum was significantly associated with seawater temperature. {P}n{TX} {G} contamination of mussels was highest in summer but persisted throughout the year. {T}his contamination was significantly associated with seawater temperature and the presence of {V}. rugosum with a time lag, but not with dissolved {P}n{TX} {G} in seawater. {B}y using the contamination model predictions and their potential variability/ uncertainty, we calculated the human acute dietary exposures throughout the year and predicted that 25% of people who consume mussels could exceed the provisional acute benchmark value during the warmest periods. {W}e suggest specific recommendations to monitor {V}. rugosum and {P}n{TX} {G}.},
  keywords = {{V}ulcanodinium rugosum ; {P}innatoxins ; {E}nvironmental determinism ; {T}oxin persistence ; {R}isk assessment ; {M}odelling ; {FRANCE} ; {MEDITERRANEE}},
  booktitle = {},
  journal = {{H}armful {A}lgae},
  volume = {129},
  numero = {},
  pages = {102500 [15 p.]},
  ISSN = {1568-9883},
  year = {2023},
  DOI = {10.1016/j.hal.2023.102500},
  URL = {https://www.documentation.ird.fr/hor/fdi:010088578},
}