@article{fdi:010088195,
  title = {{P}revalence and associated factors of optr{A}-positive-{E}nterococcus faecalis in different reservoirs around farms in {V}ietnam},
  author = {{H}a, {H}. {T}. {A}. and {N}guyen, {P}. {T}. {L}. and {H}ung, {T}. {T}. {M}. and {T}uan, {L}. {A}. and {T}huy, {B}. {T}. and {L}ien, {T}. {H}. {M}. and {T}hai, {P}. {D}. and {T}hanh, {N}. {H}. and {B}ich, {V}. {T}. {N}. and {A}nh, {T}. {H}. and {H}anh, {N}. {T}. {H}. and {M}inh, {N}. {T}. and {T}hanh, {D}. {P}. and {M}ai, {S}. {N}. {T}. and {T}he, {H}. {C}. and {T}rung, {N}. {V}. and {T}hu, {N}. {H}. and {D}uong, {T}. {N}. and {A}nh, {D}. {D}. and {N}goc, {P}. {T}. and {B}anuls, {A}nne-{L}aure and {C}hoisy, {M}arc and van {D}oorn, {H}. {R}. and {S}uzuki, {M}. and {H}oang, {T}. {H}.},
  editor = {},
  language = {{ENG}},
  abstract = {{L}inezolid is an antibiotic of last resort for the treatment of infections caused by {G}ram-positive bacteria, including vancomycin-resistant enterococci. {E}nterococcus faecalis, a member of enterococci, is a significant pathogen in nosocomial infections. {E}. faecalis resistance to linezolid is frequently related to the presence of optr{A}, which is often co-carried with fex, phenicol exporter genes, and erm genes encoding macrolide resistance. {T}herefore, the common use of antibiotics in veterinary might promote the occurrence of optr{A} in livestock settings. {T}his is a cross-sectional study aiming to investigate the prevalence of optr{A} positive {E}. faecalis ({OPE}fs) in 6 reservoirs in farms in {H}a {N}am province, {V}ietnam, and its associated factors and to explore genetic relationships of {OPE}fs isolates. {A}mong 639 collected samples, the prevalence of {OPE}fs was highest in flies, 46.8% (51/109), followed by chickens 37.3% (72/193), dogs 33.3% (17/51), humans 18.7% (26/139), wastewater 16.4% (11/67) and pigs 11.3%, (14/80). {T}he total feeding area and total livestock unit of the farm were associated with the presence of {OPE}fs in chickens, flies, and wastewater. {A}mong 186 {OPE}fs strains, 86% were resistant to linezolid. {T}he presence of optr{A} was also related to the resistant phenotype against linezolid and levofloxacin of {E}. faecalis isolates. {C}lose genotypic relationships identified by {P}ulsed {F}ield {G}el {E}lectrophoresis between {OPE}fs isolates recovered from flies and other reservoirs including chickens, pigs, dogs, and wastewater suggested the role of flies in the transmission of antibiotic-resistant pathogens. {T}hese results provided warnings of linezolid resistance although it is not used in livestock.},
  keywords = {{E}. faecalis ; farms ; flies ; linezolid resistance ; optr{A} livestock ; {V}ietnam ; {VIET} {NAM}},
  booktitle = {},
  journal = {{A}ntibiotics},
  volume = {12},
  numero = {6},
  pages = {954 [19 ]},
  ISSN = {2079-6382},
  year = {2023},
  DOI = {10.3390/antibiotics12060954},
  URL = {https://www.documentation.ird.fr/hor/fdi:010088195},
}