@article{fdi:010088139,
  title = {{Q}uality assessment of {C}urcuma dietary supplements : complementary data from {LC}-{MS} and {H}-1 {NMR}},
  author = {{S}orng, {S}. and {B}alayssac, {S}. and {D}anoun, {S}. and {A}ssemat, {G}. and {M}irre, {A}. and {C}ristofoli, {V}. and {L}e {L}amer, {A}. {C}. and {J}ullian, {V}al{\'e}rie and {G}ilard, {V}. and {F}abre, {N}. and {M}artino, {R}. and {M}alet-{M}artino, {M}.},
  editor = {},
  language = {{ENG}},
  abstract = {{D}ue to the numerous potential health benefits of {C}urcuma, turmeric dietary supplements ({DS}) are among the top selling products. {T}o assess the quality of these formulations, thirty {C}urcuma {DS} along with five standard {C}urcuma rhizomes were analyzed with {UHPLC}-{MS} and {H}-1 {NMR}. {T}he chemometric treatment of the {UHPLC}-{MS} spectra showed a significant variability of their chemical composition that was confirmed by {H}-1 {NMR} which allowed the absolute quantification of the {C}urcuma major bioactive components, i.e. curcuminoids (curcumin, demethoxycurcumin and bisdemethoxycurcumin), and turmerones (aryl-, alpha- and beta-) as well as piperine, a commonly associated curcumin bioavailability enhancer: respectively 3.5-556, 0-8.6, 0.18-8.1 mg/capsule or tablet. {T}he comparison of the actual and claimed quantities of curcuminoids and piperine showed that 58% of the {DS} contained the expected amounts of actives.},
  keywords = {{D}ietary supplements ; {C}urcuma ; {Q}uality control ; {H}-1 {NMR} ; {UHPLC}-{HRMS} ; {M}etabolomics},
  booktitle = {},
  journal = {{J}ournal of {P}harmaceutical and {B}iomedical {A}nalysis},
  volume = {212},
  numero = {},
  pages = {114631 [22 p.]},
  ISSN = {0731-7085},
  year = {2022},
  DOI = {10.1016/j.jpba.2022.114631},
  URL = {https://www.documentation.ird.fr/hor/fdi:010088139},
}