@article{fdi:010087739,
  title = {{G}enetic diversity and population structure of {M}ycobacterium bovis at the human-animal-ecosystem interface in {F}rance : "a {O}ne {H}ealth approach"},
  author = {{A}ppegren, {A}. and {B}oschiroli, {M}. {L}. and {D}e {C}ruz, {K}. and {M}ichelet, {L}. and {H}ery-{A}rnaud, {G}. and {K}empf, {M}. and {L}anotte, {P}. and {B}emer, {P}. and {P}euchant, {O}. and {P}estel-{C}aron, {M}. and {S}kalli, {S}. and {B}rasme, {L}. and {M}artin, {C}. and {E}nault, {C}. and {C}arricajo, {A}. and {G}uet-{R}evillet, {H}. and {P}onsoda, {M}. and {J}acomo, {V}. and {B}ourgoin, {A}. and {T}rombert-{P}aolantoni, {S}. and {C}arriere, {C}. and {D}upont, {C}. and {C}onquet, {G}. and {G}alal, {L}okman and {B}anuls, {A}nne-{L}aure and {G}odreuil, {S}.},
  editor = {},
  language = {{ENG}},
  abstract = {{M}ycobacterium bovis infects cattle and wildlife, and also causes a small proportion of tuberculosis cases in humans. {I}n most {E}uropean countries, {M}. bovis infections in cattle have been drastically reduced, but not eradicated. {H}ere, to determine the {M}. bovis circulation within and between the human, cattle, and wildlife compartments, we characterized by spoligotyping and mycobacterial interspersed repetitive unit-variable number tandem repeat ({MIRU}-{VNTR}) typing the genetic diversity of {M}. bovis isolates collected from humans, cattle, and wildlife in {F}rance from 2000 to 2010. {W}e also assessed their genetic structure within and among the different host groups, and across time and space. {T}he {M}. bovis genetic structure and its spatiotemporal variations showed different dynamics in the human and animal compartments. {M}ost genotypes detected in human isolates were absent in cattle and wildlife isolates, possibly because in patients, {M}. bovis infection was contracted abroad or was the reactivation of an old lesion. {T}herefore, they did not match the genetic pool present in {F}rance during the study period. {H}owever, some human-cattle exchanges occurred because some genotypes were common to both compartments. {T}his study provides new elements for understanding {M}. bovis epidemiology in {F}rance, and calls for increased efforts to control this pathogen worldwide.},
  keywords = {bovine tuberculosis ; population genetics ; zoonosis ; {O}ne {H}ealth ; {F}rance ; {FRANCE}},
  booktitle = {},
  journal = {{P}athogens},
  volume = {12},
  numero = {4},
  pages = {548 [20 ]},
  year = {2023},
  DOI = {10.3390/pathogens12040548},
  URL = {https://www.documentation.ird.fr/hor/fdi:010087739},
}