Vittecoq M. auteur aut IRD Elguero Eric auteur aut IRD Brazier L. auteur aut IRD Renaud N. auteur aut IRD Blanchon T. auteur aut IRD Roux F. auteur aut IRD Renaud F. auteur aut IRD Durand P. auteur aut IRD Thomas F. auteur aut IRD text journalArticle eng text/pdf born digital access It is increasingly suggested that the dynamics of antimicrobial-resistant bacteria in the wild are mostly anthropogenically driven, but the spatial and temporal scales at which these phenomena occur in landscapes are only partially understood. Here, we explore this topic by studying antimicrobial resistance in the commensal bacteria from micromammals sampled at 12 sites from a large heterogenous landscape (the Carmargue area, Rhone Delta) along a gradient of anthropization: natural reserves, rural areas, towns, and sewage-water treatment plants. There was a positive relationship between the frequency of antimicrobial-resistant bacteria and the level of habitat anthropization. Although low, antimicrobial resistance was also present in natural reserves, even in the oldest one, founded in 1954. This study is one of the first to support the idea that rodents in human-altered habitats are important components of the environmental pool of resistance to clinically relevant antimicrobials and also that a "One Health" approach is required to assess issues related to antimicrobial resistance dynamics in anthropized landscapes. specialized Antimicrobial resistance Landscape Rodents Bacteria Anthropization FRANCE CAMARGUE 082 080 050 021 [Early access] [9 p.] 2023 1612-9202 https://www.documentation.ird.fr/hor/fdi:010087723 10.1007/s10393-023-01638-7 1612-9202 [F B010087723] https://www.documentation.ird.fr/hor/fdi:010087723 https://www.documentation.ird.fr/intranet/publi/2023-06/010087723.pdf Accès réservé (Intranet de l'IRD) IRD - Base Horizon / Pleins textes 2023-06-30 2025-02-24 fdi:010087723 fre