@article{fdi:010087702, title = {{W}hole-genome characterization of {SARS}-{C}o{V}-2 reveals simultaneous circulation of three variants and a putative recombination (20{B}/20{H}) in pets, {B}razzaville, {R}epublic of the {C}ongo}, author = {{L}enguiya, {L}. {H}. and {F}ritz, {M}atthieu and {D}e {F}onclare, {D}. {D}. and {C}orbet, {S}. and {B}ecquart, {P}ierre and {M}bou, {C}. and {N}guie, {R}. {J}. and {M}ouellet, {W}. {S}. and {D}emboux, {J}. {E}. {L}. and {N}'{K}aya-{T}obi, {P}. and {M}ayengue, {P}. {I}. and {K}oukouikila-{K}oussounda, {F}. and {G}ouilh, {M}. {A}. and {L}eroy, {E}ric and {N}iama, {F}. {R}.}, editor = {}, language = {{ENG}}, abstract = {{F}ollowing the emergence of {SARS}-{C}o{V}-2, cases of pets infected with variants circulating among humans were reported. {I}n order to evaluate the occurrence of {SARS}-{C}o{V}-2 circulation among pets in the {R}epublic of the {C}ongo, we conducted a ten-month study of dogs and cats living in {COVID}-19-positive households in {B}razzaville and neighboring localities. {R}eal-time {PCR} and the {L}uminex platform were used to detect {SARS}-{C}o{V}-2 {RNA} and antibodies to {SARS}-{C}o{V}-2 {RBD} and {S} proteins, respectively. {O}ur results show for the first time the simultaneous circulation of several variants of {SARS}-{C}o{V}-2, including viruses from clades 20{A} and 20{H} and a putative recombinant variant between viruses from clades 20{B} and 20{H}. {W}e found a high seroprevalence of 38.6%, with 14% of tested pets positive for {SARS}-{C}o{V}-2 {RNA}. {T}hirty-four percent of infected pets developed mild clinical signs, including respiratory and digestive signs, and shed the virus for about one day to two weeks. {T}hese results highlight the potential risk of {SARS}-{C}o{V}-2 interspecies transmission and the benefits of a "{O}ne {H}ealth" approach that includes {SARS}-{C}o{V}-2 diagnosis and surveillance of viral diversity in pets. {T}his approach aims to prevent transmission to surrounding wildlife as well as spillback to humans.}, keywords = {{SARS}-{C}o{V}-2 ; pets ; cats ; dogs ; {RT}-q{PCR} ; serology ; {NGS} ; {R}epublic of the {C}ongo ({R}o{C}) ; {CONGO} ; {BRAZZAVILLE}}, booktitle = {}, journal = {{V}iruses}, volume = {15}, numero = {4}, pages = {933 [14 ]}, year = {2023}, DOI = {10.3390/v15040933}, URL = {https://www.documentation.ird.fr/hor/fdi:010087702}, }