@article{fdi:010087697,
  title = {{I}dentification of {B}ulinus forskalii as a potential intermediate host of {S}chistosoma haematobium in {S}enegal},
  author = {{G}aye, {P}. {M}. and {D}oucour{\'e}, {S}ouleymane and {S}ow, {D}. and {S}okhna, {C}heikh and {R}anque, {S}.},
  editor = {},
  language = {{ENG}},
  abstract = {{A}uthor summary{S}chistosomiasis is one of the most important neglected tropical diseases in the world. {I}t is caused by blood flukes of the genus {S}chistosoma. {I}n {S}enegal, the species {S}chistosoma h {AE} matobium is the most widespread and responsible for urinary {S}chistosomiasis in humans. {F}reshwater snails of the genus {B}ulinus including {B}ulinus truncatus, {B}ulinus globosus, {B}ulinus senegalensis and {B}ulinus umbilicatus are its main intermediate hosts. {H}owever, {B}ulinus forskalii, morphologically similar to {B}ulinus senegalensis is also frequently found but no study has ever mentioned its sensibility to {S}. h {AE} matobium in {S}enegal. {T}he aim of our research is to reveal the relevance of {B}ulinus forskalii as a potential intermediate host of {S}. h {AE} matobium but also to provide an accurate identification of this snail. {T}his study demonstrated the susceptibility of {B}ulinus forskalii to the {S}. h {AE} matobium parasite in {S}enegal by using innovative and refined identification methods to discriminate this snail and to characterize its infection. {T}his result significantly contributes to the improvement of our knowledge on host-parasite interactions and should be taken into account in future epidemiological studies and schistosomiasis control programs. {U}nderstanding the transmission of {S}chistosoma h {AE} matobium in the {S}enegal {R}iver {D}elta requires knowledge of the snails serving as intermediate hosts. {A}ccurate identification of both the snails and the infecting {S}chistosoma species is therefore essential. {C}ercarial emission tests and multi-locus ({COX}1 and {ITS}) genetic analysis were performed on {B}ulinus forskalii snails to confirm their susceptibility to {S}. h {AE} matobium infection. {A} total of 55 {B}ulinus forskalii, adequately identified by {MALDI}-{TOF} mass spectrometry, were assessed. {C}ercarial shedding and {RT}-{PCR} assays detected 13 (23.6%) and 17 (31.0%), respectively, {B}ulinus forskalii snails parasitized by {S}. h {AE} matobium complex fluke. {N}ucleotide sequence analysis identified {S}. h {AE} matobium in 6 (11.0%) using {COX}1 and 3 (5.5%) using {ITS}2, and {S}. bovis in 3 (5.5%) using {COX}1 and 3 (5.5%) using {ITS}2. {T}his result is the first report of infection of {B}ulinus forskalii by {S}. h {AE} matobium complex parasites in {S}enegal using innovative and more accurate identification methods to discriminate this snail and characterize its infection by {S}. h {AE} matobium.},
  keywords = {{SENEGAL}},
  booktitle = {},
  journal = {{PL}o{S} {N}eglected {T}ropical {D}iseases},
  volume = {17},
  numero = {5},
  pages = {e0010584 [12 p.]},
  ISSN = {1935-2735},
  year = {2023},
  DOI = {10.1371/journal.pntd.0010584},
  URL = {https://www.documentation.ird.fr/hor/fdi:010087697},
}