@article{fdi:010087464, title = {{O}micron-{BA}.1 dispersion rates in {M}exico varied according to the regional epidemic patterns and the diversity of local delta subvariants}, author = {{Z}arate, {S}. and {T}aboada, {B}. and {R}osales-{R}ivera, {M}. and {G}arcia-{L}opez, {R}. and {M}unoz-{M}edina, {J}. {E}. and {S}anchez-{F}lores, {A}. and {H}errera-{E}strella, {A}. and {G}omez-{G}il, {B}. and {M}ojica, {N}. {S}. and {S}alas-{L}ais, {A}. {G}. and {V}azquez-{P}erez, {J}. {A}. and {C}abrera-{G}aytan, {D}. {A}. and {F}ernandes-{M}atano, {L}. and {U}ribe-{N}oguez, {L}. {A}. and {C}hale-{D}zul, {J}. {B}. and {M}eza, {B}. {I}. {M}. and {M}ejia-{N}epomuceno, {F}. and {P}erez-{P}adilla, {R}. and {G}utierrez-{R}ios, {R}. {M}. and {L}oza, {A}. and {R}oche, {B}enjamin and {L}opez, {S}. and {A}rias, {C}. {F}.}, editor = {}, language = {{ENG}}, abstract = {{P}urpose: {T}he {O}micron subvariant {BA}.1 of {SARS}-{C}o{V}-2 was first detected in {N}ovember 2021 and quickly spread worldwide, displacing the {D}elta variant. {I}n this work, a characterization of the spread of this variant in {M}exico is presented. {M}ethods: {T}he time to fixation of {BA}.1, the diversity of {D}elta sublineages, the population density, and the level of virus circulation during the inter-wave interval were determined to analyze differences in {BA}.1 spread. {R}esults: {BA}.1 began spreading during the first week of {D}ecember 2021 and became dominant in the next three weeks, causing the fourth {COVID}-19 epidemiological surge in {M}exico. {U}nlike previous variants, {BA}.1 did not exhibit a geographically distinct circulation pattern. {H}owever, a regional difference in the speed of the replacement of the {D}elta variant was observed. {C}onclusions: {V}iral diversity and the relative abundance of the virus in a particular area around the time of the introduction of a new lineage seem to have influenced the spread dynamics, in addition to population density. {N}onetheless, if there is a significant difference in the fitness of the variants, or if the time allowed for the competition is sufficiently long, it seems the fitter virus will eventually become dominant, as observed in the eventual dominance of the {BA}.1.x variant in {M}exico.}, keywords = {genomic epidemiology ; {SARS}-{C}o{V}-2 ; {O}micron variant ; {D}elta variant ; viral dynamics ; diversity ; {MEXIQUE}}, booktitle = {}, journal = {{V}iruses}, volume = {15}, numero = {1}, pages = {243 [14 p.]}, year = {2023}, DOI = {10.3390/v15010243}, URL = {https://www.documentation.ird.fr/hor/fdi:010087464}, }