@article{fdi:010087419,
  title = {{P}opulation-based sero-epidemiological investigation of the dynamics of {SARS}-{C}o{V}-2 infections in the {G}reater {A}ccra {R}egion of {G}hana},
  author = {{M}ensah, {B}. {A}. and {N}dong, {I}. {C}. and {Q}uashie, {P}. {K}. and {G}uichet, {E}. and {A}buaku, {B}. and {E}ffah-{B}aafi, {Y}. and {T}apela, {K}. and {A}siedu, {K}. and {A}ppiedu-{A}ddo, {S}. {N}. {A}. and {O}bbeng, {L}. {B}. and {A}mponsah, {J}. {A}. and {K}usi, {K}. {A}. and {O}fori, {M}. and {A}youba, {A}hidjo and {C}ourtin, {D}avid and {T}ahar, {R}achida and {D}elaporte, {E}. and {A}wandare, {G}. and {T}uikue {N}dam, {N}icaise},
  editor = {},
  language = {{ENG}},
  abstract = {{T}he coronavirus disease 2019 ({COVID}-19) pandemic devastated countries worldwide, and resulted in a global shutdown. {N}ot all infections are symptomatic and hence the extent of {SARS}-{C}o{V}-2 infection in the community is unknown. {T}he paper presents the dynamics of the {SARS}-{C}o{V}-2 epidemic in the {G}reater {A}ccra {M}etropolis, describing the evolution of seroprevalence through time and by age group. {T}hree repeated independent population-based surveys at 6-week intervals were conducted in from {N}ovember 2020 to {J}uly 2021. {T}he global and by age-groups weighted seroprevalences were estimated and the risk factors for {SARS}-{C}o{V}-2 antibody seropositivity were assessed using logistic regression. {T}he overall age-standardized {SARS}-{C}o{V}-2 antibody seroprevalence for both spike and nucleocapsid increased from 13.8% (95% {CI} 11.9, 16.1) in {N}ovember 2020 to 39.6% (95% {CI} 34.8, 44.6) in {J}uly 2021. {A}fter controlling for gender, marital status, education level, and occupation, the older age group over 40 years had a higher odds of seropositivity than the younger age group ({OR} 3.0 [95% {CI} 1.1-8.5]) in the final survey. {P}upils or students had 3.3-fold increased odds of seropositivity ({OR} 3.2 [95% {CI} 1.1-8.5]) compared to the unemployed. {T}his study reinforces that, {SARS}-{C}o{V}-2 infections have been significantly higher than reported.},
  keywords = {{GHANA} ; {ACCRA}},
  booktitle = {},
  journal = {{S}cientific {R}eports - {N}ature},
  volume = {12},
  numero = {1},
  pages = {21582 [9 ]},
  ISSN = {2045-2322},
  year = {2022},
  DOI = {10.1038/s41598-022-25598-0},
  URL = {https://www.documentation.ird.fr/hor/fdi:010087419},
}