@article{fdi:010086997,
  title = {{H}igh-frequency synthetic apomixis in hybrid rice},
  author = {{V}ernet, {A}. and {M}eynard, {D}. and {L}ian, {Q}. {C}. and {M}ieulet, {D}. and {G}ibert, {O}. and {B}issah, {M}. and {R}ivallan, {R}. and {A}utran, {D}aphn{\'e} and {L}eblanc, {O}livier and {M}eunier, {A}. {C}. and {F}rouin, {J}. and {T}aillebois, {J}. and {S}hankle, {K}. and {K}handay, {I}. and {M}ercier, {R}. and {S}undaresan, {V}. and {G}uiderdoni, {E}.},
  editor = {},
  language = {{ENG}},
  abstract = {{I}ntroducing asexual reproduction through seeds - apomixis - into crop species could revolutionize agriculture by allowing {F}1 hybrids with enhanced yield and stability to be clonally propagated. {E}ngineering synthetic apomixis has proven feasible in inbred rice through the inactivation of three genes ({M}i{M}e), which results in the conversion of meiosis into mitosis in a line ectopically expressing the {BABYBOOM}1 ({BBM}1) parthenogenetic trigger in egg cells. {H}owever, only 10-30% of the seeds are clonal. {H}ere, we show that synthetic apomixis can be achieved in an {F}1 hybrid of rice by inducing {M}i{M}e mutations and egg cell expression of {BBM}1 in a single step. {W}e generate hybrid plants that produce more than 95% of clonal seeds across multiple generations. {C}lonal apomictic plants maintain the phenotype of the {F}1 hybrid along successive generations. {O}ur results demonstrate that there is no barrier to almost fully penetrant synthetic apomixis in an important crop species, rendering it compatible with use in agriculture. {P}reviously, a proof-of-concept for low frequency synthetic apomixis was established in a laboratory strain of rice by combining {M}i{M}e mutations with the egg cell expression of the embryogenic trigger - {BBM}1. {H}ere, the authors achieve clonal seed formation in hybrid rice with almost full penetrance and higher fertility.},
  keywords = {},
  booktitle = {},
  journal = {{N}ature {C}ommunications},
  volume = {13},
  numero = {1},
  pages = {7963 [13 p.]},
  year = {2022},
  DOI = {10.1038/s41467-022-35679-3},
  URL = {https://www.documentation.ird.fr/hor/fdi:010086997},
}