@article{fdi:010086951,
  title = {{E}valuation of antibody responses to tsetse fly saliva in domestic animals in the sleeping sickness endemic foci of {B}onon and {S}infra, {C}ote d'{I}voire},
  author = {{S}omda, {M}. {B}. and {N}'{D}jetchi, {M}. {K}. and {K}abor{\'e}, {J}. and {I}lboudo, {H}. and {D}ama, {E}. and {B}oma, {S}. and {C}ourtin, {F}abrice and {P}oinsignon, {A}nne and {B}engaly, {Z}. and {R}emou{\'e}, {F}ranck and {B}elem, {A}. {M}. {G}. and {B}ucheton, {B}runo and {J}amonneau, {V}incent and {K}offi, {M}.},
  editor = {},
  language = {{ENG}},
  abstract = {{A}fter intensive control efforts, human {A}frican trypanosomiasis ({HAT}) was declared eliminated in {C}ote d'{I}voire as a public health problem in {D}ecember 2020 and the current objective is to achieve the interruption of the transmission (zero cases). {R}eaching this objective could be hindered by the existence of an animal reservoir of {T}rypanosoma ({T}.) brucei (b.) gambiense. {I}n the framework of a study led in 2013 to assess the role of domestic animals in the epidemiology of {HAT} in the two last active foci from {C}ote d'{I}voire ({B}onon and {S}infra), plasmas were sampled from four species of domestic animals for parasitological (microscopic examination by the buffy coat technique ({BCT})), serological (immune trypanolysis ({TL})) and molecular (specific {PCR}: {TBR} for {T}. brucei s.l., {TCF} for {T}. congolense forest type, {TVW} for {T}. vivax and {PCR} for {T}. b. gambiense) testing. {I}n order to improve the understanding of the involvement/role of these animals in the transmission of {T}. b. gambiense, we have quantified in this study the {I}g{G} response to whole saliva extracts of {G}lossina palpalis gambiensis in order to perform an association analysis between anti-saliva responses and the positivity of diagnostic tests. {C}attle and pigs had significantly higher rates of anti-tsetse saliva responses compared to goats and sheep (p < 0.01). {I}n addition, the anti-tsetse saliva responses were strongly associated with the parasitology ({BCT}+), serology ({TL}+) and {PCR} ({TBR}+ and {TCF}+) results (p < 0.001). {T}hese associations indicate a high level of contacts between the positive/ infected animals and tsetse flies. {O}ur findings suggest that protecting cattle and pigs against tsetse bites could have a significant impact in reducing transmission of both animal and human trypanosome species, and advocates for a "{O}ne health" approach to better control {A}frican trypanosomosis in {C}ote d'{I}voire.},
  keywords = {{T}rypanosoma brucei gambiense ; {A}nimal reservoirs ; {T}setse fly ; {B}iomarker of exposure ; {C}ote d'{I}voire ; {COTE} {D}'{IVOIRE}},
  booktitle = {},
  journal = {{V}eterinary {P}arasitology : {R}egional {S}tudies and {R}eports},
  volume = {34},
  numero = {},
  pages = {100773 [5 p.]},
  ISSN = {2405-9390},
  year = {2022},
  DOI = {10.1016/j.vprsr.2022.100773},
  URL = {https://www.documentation.ird.fr/hor/fdi:010086951},
}