@article{fdi:010086917,
  title = {{S}patial distribution and physicochemical properties of respirable volcanic ash from the 16-17 august 2006 {T}ungurahua eruption ({E}cuador), and alveolar epithelium response in-vitro},
  author = {{E}ychenne, {J}. and {G}urioli, {L}. and {D}amby, {D}. and {B}elville, {C}. and {S}chiavi, {F}ederica and {M}arceau, {G}. and {S}zczepaniak, {C}. and {B}lavignac, {C}. and {L}aumonier, {M}. and {G}ardes, {E}. and {L}e {P}ennec, {J}ean-{L}uc and {N}edelec, {J}. {M}. and {B}lanchon, {L}. and {S}apin, {V}.},
  editor = {},
  language = {{ENG}},
  abstract = {{T}ungurahua volcano ({E}cuador) intermittently emitted ash between 1999 and 2016, enduringly affecting the surrounding rural area and its population, but its health impact remains poorly documented. {W}e aim to assess the respiratory health hazard posed by the 16-17 {A}ugust 2006 most intense eruptive phase of {T}ungurahua. {W}e mapped the spatial distribution of the health-relevant ash size fractions produced by the eruption in the area impacted by ash fallout. {W}e quantified the mineralogy, composition, surface texture, and morphology of a respirable ash sample isolated by aerodynamic separation. {W}e then assessed the cytotoxicity and pro-inflammatory potential of this respirable ash toward lung tissues in-vitro using {A}549 alveolar epithelial cells, by electron microscopy and biochemical assays. {T}he eruption produced a high amount of inhalable and respirable ash (12.0-0.04 kg/m(2) of sub-10 mu m and 5.3-0.02 kg/m(2) of sub-4 mu m ash deposited). {T}heir abundance and proportion vary greatly across the deposit within the first 20 km from the volcano. {T}he respirable ash is characteristic of an andesitic magma and no crystalline silica is detected. {M}orphological features and surface textures are complex and highly variable, with few fibers observed. {I}n-vitro experiments show that respirable volcanic ash is internalized by {A}549 cells and processed in the endosomal pathway, causing little cell damage, but resulting in changes in cell morphology and membrane texture. {T}he ash triggers a weak pro-inflammatory response. {T}hese data provide the first understanding of the respirable ash hazard near {T}ungurahua and the extent to which it varies spatially in a fallout deposit.},
  keywords = {{EQUATEUR}},
  booktitle = {},
  journal = {{G}eohealth},
  volume = {6},
  numero = {12},
  pages = {e2022{GH}000680 [21 ]},
  ISSN = {2471-1403},
  year = {2022},
  DOI = {10.1029/2022gh000680},
  URL = {https://www.documentation.ird.fr/hor/fdi:010086917},
}