Avahoundje E. M. auteur aut IRD Dossou J. P. auteur aut IRD Vigan A. auteur aut IRD Gaye I. auteur aut IRD Agossou C. auteur aut IRD Boyi C. auteur aut IRD Bello K. auteur aut IRD Mikponhoue J. auteur aut IRD Ba M. F. auteur aut IRD Faye A. auteur aut IRD Ridde Valéry auteur aut IRD text journalArticle eng text/pdf reformatted digital access Introduction: The development of COVID-19 vaccines has brought considerable hope for the control of the pandemic. With a view to promoting good vaccine coverage, this study aimed to measure vaccine inten-tion against COVID-19 and to understand the factors that promote it. Method: In April 2021, we conducted a cross-sectional and analytical study at the national level through a telephone survey of Beninese aged 18 years or older. We used a marginal quota sampling method (n = 865) according to age, gender, and department. We constructed the questionnaire using a theoretical framework of health intention. We determined the factors associated with intention to vaccinate against COVID-19 in Benin using a multinomial logistic regression at the 5 % significance level.Results: The intention to vaccinate was 64.7 %; 10.9 % of the population were hesitant, and 24.4 % did not want to vaccinate. Thinking that it was important to get vaccinated (AOR = 0.274; CI = 0.118-0.638) or that getting vaccinated will help protect loved ones from the virus (AOR = 0.399; CI = 0.205-0.775) increased the intention to vaccinate. Having a high level of education (AOR = 1.988; CI = 1.134-3.484), thinking that the vaccine could put one's health at risk (AOR = 2.259; CI = 1.114-4.578), and hearing something negative about the vaccine (AOR = 1.765; CI = 1.059-2.941) reduced intention to vaccinate. In addition, believing that the creators of the vaccine had ensured its safety (AOR = 0.209; CI = 0.101- 0.430), and believing that it was unlikely to be infected after vaccination (AOR = 0.359; CI = 0.183- 0.703) decreased hesitancy in favour of the intention to vaccinate. Conclusion: In April 2021, vaccine intention was high, but maintaining this high rate requires building confidence in the vaccine and combating misinformation about the vaccine. specialized Benin COVID-19 Intention Vaccine BENIN 056 12 100237 [9 ] 2022 2590-1362 https://www.documentation.ird.fr/hor/fdi:010086758 10.1016/j.jvacx.2022.100237 2590-1362 [F B010086758] https://www.documentation.ird.fr/hor/fdi:010086758 https://horizon.documentation.ird.fr/exl-doc/pleins_textes/2023-02/010086758.pdf IRD - Base Horizon / Pleins textes 2023-02-08 2025-02-24 fdi:010086758 fre