@article{fdi:010086736, title = {{U}ptake, acceptability and interpretability of 3-in-1 rapid blood self-testing for {HIV}, hepatitis {B} and hepatitis {C}}, author = {{S}alvadori, {N}. and {A}chalapong, {J}. and {B}oontan, {C}. and {P}iriya, {C}. and {A}runothong, {S}. and {N}angola, {S}. and {K}loypan, {C}. and {P}rompunt, {E}. and {K}hamduang, {W}. and {M}oolnoi, {P}. and {P}ornprasert, {S}. and {O}ngwandee, {S}. and {M}ary, {J}. {Y}. and {J}ourdain, {G}onzague and {N}go-{G}iang-{H}uong, {N}icole}, editor = {}, language = {{ENG}}, abstract = {{I}ntroduction{E}arly diagnosis is key to achieving the goal of eliminating transmission of {HIV} and hepatitis {B} and {C}. {W}e assessed the uptake, acceptability and interpretability of self-testing using a 3-in-1 rapid diagnostic test ({RDT}) in facility-based services. {M}ethods{S}tand-alone testing services were provided free of charge to consenting individuals aged >= 15 years in five facilities in northern {T}hailand. {C}lients were invited to choose between self-testing by fingerprick or venepuncture by a healthcare worker ({HCW}). {I}n each facility, several clients could simultaneously self-test in separate private areas using {T}ri{Q}uik ({TM}) ({G}enlantis, {S}an {D}iego, {CA}, {USA}), a single immunochromatographic cassette detecting {HIV}-1/2 antibody, hepatitis {B} surface antigen ({HB}s{A}g) and hepatitis {C} antibody ({HCA}b). {A}n interactive program on a tablet computer was developed to collect socio-demographic, behavioural and satisfaction data and provide information to guide the self-test process, including video instructions, results interpretation and a picture of the cassette for immediate remote review by the {HCW}. {W}hen the {HCW} interpreted an {HIV} self-test as positive, the {HCW} collected blood by venepuncture for immediate confirmation. {R}esults{B}etween {O}ctober 2020 and {A}pril 2022, 4119 clients presented for testing for the first time as part of the project. {O}f them, 3462 (84.0%) opted for self-testing. {A}mong self-testers, 1801 (52.0%) were born female, the median age was 27 years (interquartile range, 22-36), 661 (19.1%) belonged to at least one key population and 2124 (61.4%) had never been tested for {HIV}; 3329 (99.8% of those who answered) reported being "very satisfied" or "satisfied" with the testing process. {T}he proportions of test results interpreted as positive by self-testers among those interpreted as positive by {HCW}s were 95% for {HIV}-1/2 antibody, 95% for {HB}s{A}g and 78% for {HCA}b. {C}onclusions{T}hese proportions were higher than those observed in a previous study evaluating another 3-in-1 {RDT} for {HIV}, {HB}s{A}g and {HCA}b, possibly due to the use of video instructions instead of paper-based instructions, lower prevalence and co-infection rates, or lower percentages of clients with low education level. {M}ultiplex self-testing simplified and streamlined the service delivery process and was well accepted. {HCW} assistance proved to be essential in a limited number of cases.}, keywords = {hepatitis {B} ; hepatitis {C} ; {HIV} ; point-of-care testing ; rapid diagnostic ; test ; self-testing ; {THAILANDE}}, booktitle = {}, journal = {{J}ournal of the {I}nternational {AIDS} {S}ociety}, volume = {25}, numero = {12}, pages = {e26053 [6 ]}, year = {2022}, DOI = {10.1002/jia2.26053}, URL = {https://www.documentation.ird.fr/hor/fdi:010086736}, }