@article{fdi:010086660, title = {{C}hanges in onchocerciasis {O}v16 {I}g{G}4 rapid diagnostic test results over one-month follow-up : lessons for reading timeframe and decision-making}, author = {{N}ana-{D}jeunga, {H}. {C}. and {S}icard, {C}. {M}. and {M}ogoung-{W}afo, {A}. {E}. and {C}hesnais, {C}{\'e}dric and {D}eleglise, {H}. and {T}ouka-{N}ounkeu, {R}. and {D}omche, {A}. and {G}olden, {A}. and {K}lion, {A}. {D}. and {N}utman, {T}. {B}. and {B}oussinesq, {M}ichel and {K}amgno, {J}. and {P}ion, {S}{\'e}bastien}, editor = {}, language = {{ENG}}, abstract = {{T}he {SD} {B}ioline ({R}) {I}g{G}4 rapid diagnostic test ({RDT}) detects {I}g{G}4 antibodies induced by the {O}nchocerca vol-vulus-specific antigen {O}v16. {W}e evaluated the stability of the {RDT} results over 1 month, at different time points after completion of each assay, using eluted dried blood spots collected in central {C}ameroon. {A}greement coefficients regarding positivity between 30 minutes and 24 hours, 1, 2, 3, and 4 weeks were, 96.4%, 93.4%, 93.3%, 93.2%, and 93.2%, respectively. {B}etween 30 minutes and 24 hours, 3.6% of the 15,444 tests showed inconsistent results with 81.2% of these tests changing from negative to positive, increasing {O}. volvulus antibody prevalence from 23.9% to 26.2% ({P} < 0.0001). {T}his change from negative to positive outcome was confirmed at the subsequent timepoints. {D}epending on the desired accuracy of prevalence estimates, reading time may have to be redefined more strictly.}, keywords = {}, booktitle = {}, journal = {{A}merican {J}ournal of {T}ropical {M}edicine and {H}ygiene}, volume = {107}, numero = {3}, pages = {658--661}, ISSN = {0002-9637}, year = {2022}, DOI = {10.4269/ajtmh.21-1201}, URL = {https://www.documentation.ird.fr/hor/fdi:010086660}, }