@article{fdi:010086629, title = {{K}aryotypic evolution of {H}apalomys inferred from chromosome painting : a detailed characterization contributing new insights into the ancestral murinae karyotype}, author = {{B}adenhorst, {D}. and {D}obigny, {G}authier and {R}obinson, {T}. {J}.}, editor = {}, language = {{ENG}}, abstract = {{W}e report on the construction of a comparative chromosome map between the emblematic laboratory rat, {R}attus norvegicus ({RNO}), and {D}elacour's {M}armoset rat, {H}apalomys delacouri ({HDE}), based on cross-species fluorescence in situ hybridization with {R}. norvegicus painting probes. {S}ixteen {R}. norvegicus chromosomes ({RNO} 3-6, 8, 10-15, 17-20, and {X}) were retained in their entirety (as a conserved block or as a single chromosome) in the {H}. delacouri genome. {T}he remaining 5 {R}. norvegicus chromosomes ({RNO} 1, 2, 7, 9, and 16) produced 2 signals in the {H}. delacouri karyotype. {O}ur analysis allowed the detection of an {X}-autosome translocation between {RNO} {X} and 11 that occurred convergently in an unrelated species, {B}andicota savilei, and a single {B} chromosome that accounts for the 2n = 48 karyotype observed in this specimen. {I}n total, the rat chromosome paints revealed 27 segments of conserved synteny in {H}. delacouri. {T}he analysis showed 7 {NOR} bearing pairs in {H}. delacouri ({HDE} 1, 3, 6, 7, 8, 10, and 13) and the occurrence of an interstitial telomeric signal at the centromeric regions of 8 {H}. delacouri chromosomes ({HDE} 3, 10, 11, 12, 13, 16, 19, and 22). {T}hese data, together with published comparative maps, enabled a revision of the previously postulated murine ancestral condition suggesting that it probably comprised a wholly acrocentric karyotype with 2n = 46-50.}, keywords = {{A}ncestral karyotype ; {H}apalomys delacouri ; {M}uridae ; {R}attus norvegicus ; {Z}oo-{FISH}}, booktitle = {}, journal = {{C}ytogenetic and {G}enome {R}esearch}, volume = {136}, numero = {2}, pages = {83--88}, ISSN = {1424-8581}, year = {2012}, DOI = {10.1159/000335286}, URL = {https://www.documentation.ird.fr/hor/fdi:010086629}, }