@article{fdi:010086020,
  title = {{H}epatitis {E} virus seroprevalence and associated risk factors in pregnant women attending antenatal consultations in {S}enegal},
  author = {{D}iouara, {A}. {M}. and {L}o, {S}. and {N}guer, {C}. {M}. and {S}enghor, {A}. and {N}diaye, {H}. {D}. and {M}anga, {N}. {M}. and {D}anfakha, {F}. and {D}iallo, {S}. and {D}ieme, {M}. {E}. {F}. and {T}hiam, {O}. and {B}iaye, {B}. and {M}anga, {N}. {M}. {P}. and {T}hiam, {F}. and {S}arr, {H}. and {L}o, {G}. and {N}dour, {M}. and {M}anga, {S}. {P}. and {D}iaby, {N}. and {D}ieng, {M}. and {D}iop, {I}. and {D}ieye, {Y}. and {K}ane, {C}. {T}. and {P}eeters, {M}artine and {A}youba, {A}hidjo},
  editor = {},
  language = {{ENG}},
  abstract = {{I}n {W}est {A}frica, research on the hepatitis {E} virus ({HEV}) is barely covered, despite the recorded outbreaks. {T}he low level of access to safe water and adequate sanitation is still one of the main factors of {HEV} spread in developing countries. {HEV} infection induces acute or sub-clinical liver diseases with a mortality rate ranging from 0.5 to 4%. {T}he mortality rate is more alarming (15 to 25%) among pregnant women, especially in the last trimester of pregnancy. {H}erein, we conducted a multicentric socio-demographic and seroepidemiological survey of {HEV} in {S}enegal among pregnant women. {A} consecutive and non-redundant recruitment of participants was carried out over the period of 5 months, from {M}arch to {J}uly 2021. {A} total of 1227 consenting participants attending antenatal clinics responded to a standard questionnaire. {P}lasma samples were collected and tested for anti-{HEV} {I}g{M} and {I}g{G} by using the {WANTAI} {HEV}-{I}g{M} and {I}g{G} {ELISA} assay. {T}he overall {HEV} seroprevalence was 7.8% (n = 96), with 0.5% (n = 6) and 7.4% (n = 91) for {HEV} {I}g{M} and {HEV} {I}g{G}, respectively. {O}ne of the participant samples was {I}g{M}/{I}g{G}-positive, while four were declared indeterminate to anti-{HEV} {I}g{M} as per the manufacturer's instructions. {F}rom one locality to another, the seroprevalence of {HEV} antibodies varied from 0 to 1% for {HEV} {I}g{M} and from 1.5 to 10.5% for {HEV} {I}g{G}. {T}he data also showed that seroprevalence varied significantly by marital status (p < 0.0001), by the regularity of income (p = 0.0043), and by access to sanitation services (p = 0.0006). {T}hese data could serve as a basis to setup national prevention strategies focused on socio-cultural, environmental, and behavioral aspects for a better management of {HEV} infection in {S}enegal.},
  keywords = {hepatitis {E} ; associated risk factors ; pregnant women ; environment ; prevention ; {S}enegal ; {SENEGAL} ; {DAKAR} ; {SAINT} {LOUIS} ; {ZIGUINCHOR} ; {KEDOUGOU}},
  booktitle = {},
  journal = {{V}iruses},
  volume = {14},
  numero = {8},
  pages = {1742 [12 p.]},
  year = {2022},
  DOI = {10.3390/v14081742},
  URL = {https://www.documentation.ird.fr/hor/fdi:010086020},
}