Exposure assessment of 170 pesticide ingredients and derivative metabolites in people from the Central Andes of Peru Honles J. auteur aut IRD Clisson C. auteur aut IRD Monge C. auteur aut IRD Vasquez-Ocmin P. auteur aut IRD Cerapio J. P. auteur aut IRD Palamy S. auteur aut IRD Casavilca-Zambrano S. auteur aut IRD Herrera Javier auteur aut IRD Pineau P. auteur aut IRD Deharo Eric auteur aut IRD Peynet V. auteur aut IRD Bertani Stéphane auteur aut IRD text journalArticle eng text/pdf reformatted digital access The Central Andes of Peru are a region of great concern regarding pesticide risk to the health of local communities. Therefore, we conducted an observational study to assess the level of pesticide contamination among Andean people. Analytical chemistry methods were used to measure the concentrations of 170 pesticide-related compounds in hair samples from 50 adult Andean subjects living in rural and urban areas. As part of the study, a questionnaire was administered to the subjects to collect information regarding factors that increase the risk of pesticide exposure. Our results indicate that Andean people are strongly exposed to agrochemicals, being contaminated with a wide array of pesticide-related compounds at high concentration levels. Multivariate analyses and geostatistical modeling identified sociodemographic factors associated with rurality and food origin that increase pesticide exposure risk. The present study represents the first comprehensive investigation of pesticide-related compounds detected in body samples collected from people living in the Central Andes of Peru. Our findings pinpoint an alarming environmental situation that threatens human health in the region and provide a rationale for improving public policies to protect local communities. specialized PEROU ANDES 050 038 020 Scientific Reports - Nature 12 1 13525 [15 ] 2022 2045-2322 https://www.documentation.ird.fr/hor/fdi:010085993 10.1038/s41598-022-17772-1 2045-2322 [F B010085993] https://www.documentation.ird.fr/hor/fdi:010085993 https://horizon.documentation.ird.fr/exl-doc/pleins_textes/2022-09/010085993.pdf IRD - Base Horizon / Pleins textes 2022-09-28 2025-02-24 fdi:010085993 fre