@article{fdi:010085360,
  title = {{W}arthog genomes resolve an evolutionary conundrum and reveal introgression of disease resistance genes},
  author = {{G}arcia-{E}rill, {G}. and {J}orgensen, {C}. {H}. {F}. and {M}uwanika, {V}. {B}. and {W}ang, {X}. and {R}asmussen, {M}. {S}. and de {J}ong, {Y}. {A}. and {G}aubert, {P}hilippe and {O}layemi, {A}. and {S}almona, {J}. and {B}utynski, {T}. {M}. and {B}ertola, {L}. {D}. and {S}iegismund, {H}. {R}. and {A}lbrechtsen, {A}. and {H}eller, {R}.},
  editor = {},
  language = {{ENG}},
  abstract = {{A}frican wild pigs have a contentious evolutionary and biogeographic history. {U}ntil recently, desert warthog ({P}hacochoerus aethiopicus) and common warthog ({P}. africanus) were considered a single species. {M}olecular evidence surprisingly suggested they diverged at least 4.4 million years ago, and possibly outside of {A}frica. {W}e sequenced the first whole-genomes of four desert warthogs and 35 common warthogs from throughout their range. {W}e show that these two species diverged much later than previously estimated, 400,000-1,700,000 years ago depending on assumptions of gene flow. {T}his brings it into agreement with the paleontological record. {W}e found that the common warthog originated in western {A}frica and subsequently colonized eastern and southern {A}frica. {D}uring this range expansion, the common warthog interbred with the desert warthog, presumably in eastern {A}frica, underlining this region's importance in {A}frican biogeography. {W}e found that immune system-related genes may have adaptively introgressed into common warthogs, indicating that resistance to novel diseases was one of the most potent drivers of evolution as common warthogs expanded their range. {H}ence, we solve some of the key controversies surrounding warthog evolution and reveal a complex evolutionary history involving range expansion, introgression, and adaptation to new diseases.},
  keywords = {{P}hacochoerus evolution ; introgression ; disease resistance ; {A}frican ; phylogeography ; population structure ; {AFRIQUE} ; {GHANA} ; {KENYA} ; {TANZANIE} ; {ZAMBIE} ; {ZIMBABWE} ; {NAMIBIE}},
  booktitle = {},
  journal = {{M}olecular {B}iology and {E}volution},
  volume = {39},
  numero = {7},
  pages = {msac134 [17 p.]},
  ISSN = {0737-4038},
  year = {2022},
  DOI = {10.1093/molbev/msac134},
  URL = {https://www.documentation.ird.fr/hor/fdi:010085360},
}