@article{fdi:010085117,
  title = {{C}ordiasecosides {G}-{J}, 9,10-{S}eco-29-norcycloartane glycosides isolated from {C}ordia lutea and their antibacterial activities},
  author = {{C}astro, {I}. and {A}ndre-{B}arres, {C}. and {F}abre, {N}. and {M}assou, {S}. and {S}auvain, {M}ichel and {P}areja, {D}. {C}. and {J}ullian, {V}al{\'e}rie},
  editor = {},
  language = {{ENG}},
  abstract = {{F}our undescribed secocycloartane monoglycosides (1-4) were isolated from an ethanolic extract of the dry flowers of {C}ordia lutea {L}am. {T}heir structural assignment is based on {NMR} and {MS} analysis. {T}heir stereochemistry is confirmed by molecular modelling studies using {DFT}-{NMR} calculations done for compound 3. {I}n vitro antibacterial activity of the four compounds was moderate on {H}elicobacter pylori ({MIC} = 15.6 mu g/m{L}), and much weaker on {S}taphylococcus aureus, {P}seudomonas aeruginosa or {E}scherichia coli ({MIC} >125 mu g/m{L}). {T}oxicity evaluated against {RAW} 264.7 cells was weak ({IC}50 values ranging from 24 to 41 mu {M} i.e. 15 to 24 mu g/m{L}), but in the same range as anti-{H}elicobacter activity.},
  keywords = {{C}ordia lutea ; {B}oraginaceae ; {H}elicobacter pylori ; {A}ntibacterial ; {S}ecocycloartane ; {T}raditional medicine ; {PEROU}},
  booktitle = {},
  journal = {{F}itoterapia},
  volume = {158},
  numero = {},
  pages = {105172 [6 ]},
  ISSN = {0367-326{X}},
  year = {2022},
  DOI = {10.1016/j.fitote.2022.105172},
  URL = {https://www.documentation.ird.fr/hor/fdi:010085117},
}