@article{fdi:010084776,
  title = {{G}enetic diversity of {SARS}-{C}o{V}-2 infections in {G}hana from 2020-2021},
  author = {{M}orang'a, {C}. {M}. and {N}goi, {J}. {M}. and {G}yamfi, {J}. and {A}muzu, {D}. {S}. {Y}. and {N}uertey, {B}. {D}. and {S}oglo, {P}. {M}. and {A}ppiah, {V}. and {A}sante, {I}. {A}. and {O}wusu-{O}duro, {P}. and {A}rmoo, {S}. and {A}du-{G}yasi, {D}. and {A}moako, {N}. and {O}liver-{C}ommey, {J}. and {O}wusu, {M}. and {S}ylverken, {A}. and {F}enteng, {E}. {D}. and {M}'{C}ormack, {V}. {V}. and {T}ei-{M}aya, {F}. and {Q}uansah, {E}. {B}. and {A}yivor-{D}janie, {R}. and {A}moako, {E}. {K}. and {O}gbe, {I}. {T}. and {Y}emi, {B}. {K}. and {O}sei-{W}usu, {I}. and {M}ettle, {D}. {N}. {A}. and {S}aiid, {S}. and {T}apela, {K}. and {D}zabeng, {F}. and {M}agnussen, {V}. and {Q}uaye, {J}. and {O}purum, {P}. {C}. and {C}arr, {R}. {A}. and {A}babio, {P}. {T}. and {A}bass, {A}. {K}. and {A}koriyea, {S}. {K}. and {A}moako, {E}. and {K}umi-{A}nsah, {F}. and {B}oakye, {O}. {D}. and {M}ibut, {D}. {K}. and {O}doom, {T}. and {O}fori-{B}oadu, {L}. and {A}llegye-{C}udjoe, {E}. and {D}assah, {S}. and {A}soala, {V}. and {A}sante, {K}. {P}. and {P}hillips, {R}. {O}. and {O}sei-{A}tweneboana, {M}. {Y}. and {G}yapong, {J}. {O}. and {K}uma-{A}boagye, {P}. and {A}mpofo, {W}. {K}. and {D}uedu, {K}. {O}. and {T}uikue {N}dam, {N}icaise and {B}ediako, {Y}. and {Q}uashie, {P}. {K}. and {A}menga-{E}tego, {L}. {N}. and {A}wandare, {G}. {A}.},
  editor = {},
  language = {{ENG}},
  abstract = {{T}he {COVID}-19 pandemic is one of the fastest evolving pandemics in recent history. {A}s such, the {SARS}-{C}o{V}-2 viral evolution needs to be continuously tracked. {T}his study sequenced 1123 {SARS}-{C}o{V}-2 genomes from patient isolates (121 from arriving travellers and 1002 from communities) to track the molecular evolution and spatio-temporal dynamics of the {SARS}-{C}o{V}-2 variants in {G}hana. {T}he data show that initial local transmission was dominated by {B}.1.1 lineage, but the second wave was overwhelmingly driven by the {A}lpha variant. {S}ubsequently, an unheralded variant under monitoring, {B}.1.1.318, dominated transmission from {A}pril to {J}une 2021 before being displaced by {D}elta variants, which were introduced into community transmission in {M}ay 2021. {M}utational analysis indicated that variants that took hold in {G}hana harboured transmission enhancing and immune escape spike substitutions. {T}he observed rapid viral evolution demonstrates the potential for emergence of novel variants with greater mutational fitness as observed in other parts of the world.},
  keywords = {{GHANA}},
  booktitle = {},
  journal = {{N}ature {C}ommunications},
  volume = {13},
  numero = {1},
  pages = {2494 [11 p.]},
  year = {2022},
  DOI = {10.1038/s41467-022-30219-5},
  URL = {https://www.documentation.ird.fr/hor/fdi:010084776},
}