Rate and predictors of ineffective HIV protection in African men who have sex with men taking pre-exposure prophylaxis Eubanks A. auteur aut IRD Coulibaly B. auteur aut IRD Keita B. D. auteur aut IRD Anoma C. auteur aut IRD Dah T. E. auteur aut IRD Mensah E. auteur aut IRD Maradan G. auteur aut IRD Bourrelly M. auteur aut IRD Mora M. auteur aut IRD Riegel L. auteur aut IRD Castro D. R. auteur aut IRD Yaya Issifou auteur aut IRD Spire B. auteur aut IRD Laurent Christian auteur aut IRD Sagaon Teyssier Luis auteur aut IRD CohMSM-PrEP Study Group auteur aut IRD text journalArticle eng text/pdf born digital access We investigated the rate and predictors of ineffective HIV protection in men who have sex with men (MSM) taking pre-exposure prophylaxis (PrEP) in a prospective cohort study from November 2017 to November 2020 in Mali, Cote d'Ivoire, Burkina Faso, and Togo. MSM had to be 18 years or older and at high risk of HIV infection to participate. They also received a comprehensive sexual health prevention package, including PrEP, in community-based clinics as part of the cohort study. Using socio-behavioral/clinical data, HIV protection during their most recent anal intercourse with a male partner was categorized as effective or ineffective (i.e., incorrect PrEP adherence and no condom use). Seventeen percent (500/2839) of intercourses were ineffectively protected for the 520 study participants. Predictors of ineffective HIV protection included being an event-driven user with financial difficulties, having a high alcohol misuse score, and not being a member of a community association. PrEP programs in West Africa must be tailored to socially vulnerable MSM who struggle to adopt PrEP. specialized MSM PrEP HIV Community-based research West Africa AFRIQUE DE L'OUEST MALI COTE D'IVOIRE BURKINA FASO TOGO BAMAKO ABIDJAN OUAGADOUGOU LOME 052 056 Aids and Behavior 26 11 3524-3537 2022 1090-7165 https://www.documentation.ird.fr/hor/fdi:010084712 10.1007/s10461-022-03692-8 1090-7165 [F B010084712] https://www.documentation.ird.fr/hor/fdi:010084712 https://www.documentation.ird.fr/intranet/publi/2022-06/010084712.pdf Accès réservé (Intranet de l'IRD) IRD - Base Horizon / Pleins textes 2022-06-03 2025-02-24 fdi:010084712 fre