@article{fdi:010084609, title = {{D}ynamics of antibodies to {E}bolaviruses in an {E}idolon helvum bat colony in {C}ameroon}, author = {{D}jomsi, {D}. {M}. and {D}jonzo, {F}. {A}. {M}. and {B}ass, {I}. {N}. and {C}hampagne, {M}. and {L}acroix, {A}udrey and {T}haurignac, {G}. and {E}steban, {A}mandine and {D}e {N}ys, {H}. and {B}ourgarel, {M}. and {A}koachere, {J}. {F}. and {D}elaporte, {E}. and {A}youba, {A}hidjo and {C}appelle, {J}. and {N}gole, {E}. {M}. and {P}eeters, {M}artine}, editor = {}, language = {{ENG}}, abstract = {{T}he ecology of ebolaviruses is still poorly understood and the role of bats in outbreaks needs to be further clarified. {S}traw-colored fruit bats ({E}idolon helvum) are the most common fruit bats in {A}frica and antibodies to ebolaviruses have been documented in this species. {B}etween {D}ecember 2018 and {N}ovember 2019, samples were collected at approximately monthly intervals in roosting and feeding sites from 820 bats from an {E}idolon helvum colony. {D}ried blood spots ({DBS}) were tested for antibodies to {Z}aire, {S}udan, and {B}undibugyo ebolaviruses. {T}he proportion of samples reactive with {GP} antigens increased significantly with age from 0-9/220 (0-4.1%) in juveniles to 26-158/225 (11.6-70.2%) in immature adults and 10-225/372 (2.7-60.5%) in adult bats. {A}ntibody responses were lower in lactating females. {V}iral {RNA} was not detected in 456 swab samples collected from 152 juvenile and 214 immature adult bats. {O}verall, our study shows that antibody levels increase in young bats suggesting that seroconversion to {E}bola or related viruses occurs in older juvenile and immature adult bats. {M}ultiple year monitoring would be needed to confirm this trend. {K}nowledge of the periods of the year with the highest risk of {E}bolavirus circulation can guide the implementation of strategies to mitigate spill-over events.}, keywords = {ebola ; {A}frica ; bat ; {E}idolon helvum ; {C}ameroon ; virus ; antibody ; {CAMEROUN}}, booktitle = {}, journal = {{V}iruses}, volume = {14}, numero = {3}, pages = {560 [13 p.]}, year = {2022}, DOI = {10.3390/v14030560}, URL = {https://www.documentation.ird.fr/hor/fdi:010084609}, }