@article{fdi:010084575,
  title = {{A}dded value of an anti-{E}bola serology for the management of clinically suspected {E}bola virus disease patients discharged as negative in an epidemic context},
  author = {{N}kuba-{N}daye, {A}. and {M}ukadi-{B}amuleka, {D}. and {B}ulabula-{P}enge, {J}. and {T}haurignac, {G}. and {E}didi-{A}tani, {F}. and {M}ambu-{M}bika, {F}. and {D}anga-{Y}ema, {B}. and {M}atondo-{K}uamfumu, {M}. and {K}inganda-{L}usamaki, {E}. and {B}isento, {N}. and {L}umembe-{N}umbi, {R}. and {K}abamba-{L}ungenyi, {G}. and {K}itsa-{M}utsumbirwa, {D}. and {K}ambale-{S}ivihwa, {N}. and {B}oillot, {F}. and {D}elaporte, {E}. and {M}bala-{K}ingebeni, {P}. and {A}youba, {A}hidjo and {P}eeters, {M}artine and {A}huka-{M}undeke, {S}.},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground {S}urvivors from {E}bola virus disease ({EVD}) may be at the origin of {EVD} resurgence. {M}ethods {S}imultaneous reactivity to at least 2 {E}bola virus or {Z}aire ebolavirus ({EBOV}) antigens was detected in 11 of 488 (2.3%; 95% confidence interval [{CI}], 1.1-4.0) suspected {EVD} patients who were discharged as negative after 2 consecutive negative tests during the 10th {E}bola outbreak in the {D}emocratic {R}epublic of the {C}ongo. {R}esults {A}fter extrapolating the total number of individuals discharged as negative during the entire outbreak, we estimated a total of 1314 additional missed {E}bola cases. {C}onclusions {T}hese findings emphasize the usefulness of an {EBOV} serology analysis and the importance of extending epidemic surveillance to clinically suspected cases who were discharged as negative. {I}n clinically suspected {EVD} patients, {EVD} may be missed and inadvertently cause {EBOV} resurgence. {T}hus, surveillance during and after outbreaks should be extended to {EBOV} household contacts and to patients discharged as negative with an accurate serologic assay.},
  keywords = {{DRC} ; {E}bola ; {I}turi ; {N}orth-{K}ivu ; serology ; {REPUBLIQUE} {DEMOCRATIQUE} {DU} {CONGO} ; {ITURI} ; {NORD} {KIVU}},
  booktitle = {},
  journal = {{J}ournal of {I}nfectious {D}iseases},
  volume = {[{E}arly access]},
  numero = {},
  pages = {[5 p.]},
  ISSN = {0022-1899},
  year = {2022},
  DOI = {10.1093/infdis/jiac057},
  URL = {https://www.documentation.ird.fr/hor/fdi:010084575},
}