@article{fdi:010084477, title = {{S}ustainable, healthy cities : protocol of a mixed methods evaluation of a cluster randomized controlled trial for {A}edes control in {B}razil using a community mobilization approach}, author = {{Z}inszer, {K}. and {C}aprara, {A}. and {L}ima, {A}. and {D}egroote, {S}t{\'e}phanie and {Z}ahreddine, {M}. and {A}breu, {K}. and {C}arabali, {M}. and {C}harland, {K}. and {D}antas, {M}.{A}. and {W}ellington, {J}. and {P}arra, {B}. and {F}ournet, {F}lorence and {B}onnet, {E}mmanuel and {P}{\'e}rez, {D}. and {R}obert, {E}. and {D}agenais, {C}. and {B}enmarhnia, {T}. and {A}ndresson, {N}. and {R}idde, {V}al{\'e}ry}, editor = {}, language = {{ENG}}, abstract = {{B}ackground: {D}engue is increasing in its global presence with an estimated 4 billion people at-risk of infection in at least 128 countries. {D}espite the promising results of {E}co{H}ealth and community mobilization approaches to {A}edes reduction, more evidence of their efficacy on reducing dengue risk is needed. {T}he principal research question is to determine if interventions based upon community mobilization reduce the risk of dengue virus infection among children 3 to 9 years old compared to usual dengue control practice in {F}ortaleza, {B}razil. {M}ethods: {T}he present study will follow a pragmatic cluster randomized controlled trial (c{RCT}) design with randomization at the census tract level with equal allocation to the two arms. {I}n each arm, there will be 34 clusters of 86 children between 3 to 9 years old for an expected total of 5848 children enrolled in the study, assuming a risk reduction of 29.5% based upon findings from a previous multi-site c{RCT}. {T}he primary outcomes are rates of anti-dengue {I}mmunoglobulin {G} ({I}g{G}) seroconversion and adult female {A}edes density. {T}he intervention is based upon a participatory health research approach, {S}ocializing {E}vidence for {P}articipatory {A}ction ({SEPA}), where the research evidence is used to foster community engagement and ownership of the health issue and solution. {F}ollowing allocation, intervention communities will develop and implement their own solutions that will likely include a wide variety of collective events and media approaches. {D}ata collection activities over a period of 3 years include household visits for blood collection, household surveys, and entomological surveys; and qualitative activities including focus groups, in-depth interviews, and document analysis to evaluate the process, acceptability, fidelity, and sustainability of the intervention. {S}tudy participants will be aware of their assignment and all research staff will be blinded although the intervention assignment will likely be revealed to field staff through interaction with participants. {D}iscussion: {T}he results of our study will provide evidence on community mobilization as an intervention for dengue control. {W}e anticipate that if community mobilization is effective in {F}ortaleza, the results of this study will help develop evidence-based vector control programs in {B}razil, and also in other countries struggling with {A}edes-transmitted diseases.}, keywords = {{BRESIL} ; {FORTALEZA}}, booktitle = {}, journal = {{T}rials}, volume = {21}, numero = {1}, pages = {182 [15 ]}, ISSN = {1745-6215}, year = {2020}, DOI = {10.1186/s13063-019-3714-8}, URL = {https://www.documentation.ird.fr/hor/fdi:010084477}, }