@article{fdi:010084364,
  title = {{M}alaria in the first trimester of pregnancy and fetal growth : results from a {B}eninese preconceptional cohort},
  author = {{K}oladjo, {B}. {F}. and {Y}ovo, {E}. and {A}ccrombessi, {M}. and {A}gbota, {G}ino and {A}tade, {W}. and {L}adikpo, {O}. {T}. and {M}ehoba, {M}. and {D}egbe, {A}. and {J}ackson, {N}. and {M}assougbodji, {A}. and {S}ossou, {D}. and {V}ianou, {B}. and {C}ot, {M}ichel and {C}ottrell, {G}illes and {F}ievet, {N}adine and {Z}eitlin, {J}. and {B}riand, {V}al{\'e}rie},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground {M}alaria in early pregnancy occurs at a time when the placenta is developing, with possible consequences for placental function and fetal growth. {W}e assessed the association between first trimester malaria and fetal growth documented through repeated ultrasound scans. {M}ethods {T}he {RECIPAL} preconceptional cohort included 411 {B}eninese pregnant women followed from 7 weeks' gestation (wg) until delivery. {A}mong them, 218 had 4 scans for fetal monitoring at 16, 22, 28, and 34 wg. {M}ultivariate seemingly unrelated regression models were used to assess association of microscopic malaria in the first trimester (<15 wg) with abdominal circumference, head circumference, biparietal diameter, and femur length throughout pregnancy. {R}esults {O}f 39% (86/218) of women with at least 1 microscopic malarial infection during pregnancy, 52.3% (45/86) were infected in the first trimester. {M}ost women (88.5%) were multiparous. {T}here was no association between adjusted z-scores for fetal growth parameters and first trimester malaria. {P}arity, newborn sex, socioeconomic level, and maternal body mass index significantly influenced fetal growth. {C}onclusions {I}n a context where malaria infections in pregnancy are well detected and treated, their adverse effect on fetal growth may be limited. {O}ur results argue in favor of preventing and treating infections as early as the first trimester. {U}sing {RECIPAL} preconceptional cohort data, there was no association between first trimester malaria and fetal growth parameters throughout the pregnancy. {I}n a context where malaria is well detected and treated, its adverse effect on fetal growth may be limited.},
  keywords = {malaria ; epidemiology ; fetal growth ; {A}frica ; modeling ; {BENIN}},
  booktitle = {},
  journal = {{J}ournal of {I}nfectious {D}iseases},
  volume = {[{E}arly access]},
  numero = {},
  pages = {[9 p.]},
  ISSN = {0022-1899},
  year = {2022},
  DOI = {10.1093/infdis/jiac012},
  URL = {https://www.documentation.ird.fr/hor/fdi:010084364},
}