%0 Journal Article
%9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES
%A Villarroel, P. M. S.
%A Soto, M. D. C.
%A Undurraga, V.
%A Sanz, H.
%A Jaldin, A. M.
%A Ninove, L.
%A Nurtop, E.
%A Pezzi, L.
%A Ali, S. M.
%A Amroun, A.
%A Seston, Morgan
%A de Lamballerie, X.
%T High SARS-CoV-2 prevalence among healthcare workers in Cochabamba, Bolivia
%D 2022
%L fdi:010084360
%G ENG
%J Viruses
%K seroprevalence ; SARS-CoV-2 ; healthcare workers ; Bolivia
%K BOLIVIE ; COCHABAMBA
%M ISI:000762305600001
%N 2
%P 232 [10 ]
%R 10.3390/v14020232
%U https://www.documentation.ird.fr/hor/fdi:010084360
%> https://horizon.documentation.ird.fr/exl-doc/pleins_textes/2022-04/010084360.pdf
%V 14
%W Horizon (IRD)
%X Healthcare workers (HCWs) are at increased risk of SARS-CoV-2 infection. The aim of the study was to estimate the SARS-CoV-2 seroprevalence among HCWs in Cochabamba, Bolivia and to determine the potential risk factors. In January 2021, a cross-sectional SARS-CoV-2 seroprevalence study was conducted in 783 volunteer clinical and non-clinical HCWs in tertiary care facilities. It was based on IgG detection using ELISA, chemiluminiscence, and seroneutralisation tests from dried blood spots. Analysis revealed a high seroprevalence (43.4%) of SARS-CoV-2 IgG antibodies. The combination of anosmia and ageusia (OR: 68.11; 95%-CI 24.83-186.80) was predictive of seropositivity. Belonging to the cleaning staff (OR: 1.94; 95%-CI 1.09-3.45), having more than two children in the same house (OR: 1.74; 95%-CI 1.12-2.71), and having been in contact with a close relative with COVID-19 (OR: 3.53; 95%-CI 2.24-5.58) were identified as risk factors for seropositivity in a multivariate analysis. A total of 47.5% of participants had received medication for COVID-19 treatment or prevention, and only ~50% of symptomatic subjects accessed PCR or antigenic testing. This study confirms a massive SARS-CoV-2 attack rate among HCWs in Cochabamba by the end of January 2021. The main risk factors identified are having a low-skilled job, living with children, and having been in contact with an infected relative in the household.
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