%0 Journal Article
%9 ACL : Articles dans des revues avec comité de lecture répertoriées par l'AERES
%A Pion, Sébastien
%A Chesnais, Cédric
%A Weil, G. J.
%A Louya, F.
%A Boussinesq, Michel
%A Missamou, F.
%T Impact of semi-annual albendazole on lymphatic filariasis and soil-transmitted helminth infection : parasitological assessment after 14 rounds of community treatment
%D 2022
%L fdi:010084346
%G ENG
%J American Journal of Tropical Medicine and Hygiene
%@ 0002-9637
%K CONGO
%M ISI:000762022500034
%N 2
%P 729-731
%R 10.4269/ajtmh.21-0731
%U https://www.documentation.ird.fr/hor/fdi:010084346
%> https://horizon.documentation.ird.fr/exl-doc/pleins_textes/2022-04/010084346.pdf
%V 106
%W Horizon (IRD)
%X Between October 2012 and October 2015, we conducted a community trial to assess the impact of semi-annual (twice yearly) community treatment with albendazole on lymphatic filariasis in Seke Pembe, a village in the Republic of the Congo. Semi-annual community treatment with albendazole has been continued in the community since October 2015. We conducted an additional parasitological assessment survey in October 2019, 6 months after the 14th round of semi-annual treatment. Between October 2012 and October 2015, Wuchereria bancrofti antigenemia and microfilaremia rates in the community had decreased from 17.3% to 4.7% and from 5.3% to 0.3%, respectively. In October 2019, the antigenemia rate had decreased further to 2.8% (19 of 687). No microfilariae were found in night blood smears from persons with circulating filarial antigenemia (0 of 16), suggesting that W. bancrofti transmission has been interrupted in Seke Pembe. Semi-annual albendazole treatments also reduced significantly infection rates with soil transmitted helminths.
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