@article{fdi:010084328,
  title = {{F}easibility of a randomized clinical trial evaluating a community intervention for household tuberculosis child contact management in {C}ameroon and {U}ganda},
  author = {{V}asiliu, {A}nca and {T}iendrebeogo, {G}. and {A}wolu, {M}. {M}. and {A}katukwasa, {C}. and {T}chakounte, {B}. {Y}. and {S}sekyanzi, {B}. and {T}chounga, {B}. {K}. and {A}twine, {D}. and {C}asenghi, {M}. and {B}onnet, {M}aryline and {CONTACT} {S}tudy {G}roup},
  editor = {},
  language = {{ENG}},
  abstract = {{B}ackground: {O}ne of the main barriers of the management of household tuberculosis child contacts is the necessity for parents to bring healthy children to the facility. {W}e assessed the feasibility of a community intervention for tuberculosis ({TB}) household child contact management and the conditions for its evaluation in a cluster randomized controlled trial in {C}ameroon and {U}ganda. {M}ethods: {W}e assessed three dimensions of feasibility using a mixed method approach: (1) recruitment capability using retrospective aggregated data from facility registers; (2) acceptability of the intervention using focus group discussions with {TB} patients and in-depth interviews with healthcare providers and community leaders; and (3) adaptation, integration, and resources of the intervention in existing {TB} services using a survey and discussions with stakeholders. {R}esults: {R}eaching the sample size is feasible in all clusters in 15 months with the condition of regrouping 2 facilities in the same cluster in {U}ganda due to decentralization of {TB} services. {C}ommunity health worker ({CHW}) selection and training and simplified tools for contact screening, tolerability, and adherence of preventive therapy were key elements for the implementation of the community intervention. {H}ealthcare providers and patients found the intervention of child contact investigations and {TB} preventive treatment management in the household acceptable in both countries due to its benefits (competing priorities, transport cost) as compared to facility-based management. {TB} stigma was present, but not a barrier for the community intervention. {V}isit schedule and team conduct were identified as key facilitators for the intervention. {C}onclusions: {T}his study shows that evaluating a community intervention for {TB} child contact management in a cluster randomized trial is feasible in {C}ameroon and {U}ganda.},
  keywords = {{P}ediatric tuberculosis ; {C}ommunity intervention ; {T}uberculosis preventive therapy ; {T}uberculosis screening ; {A}ctive contact investigation ; {F}easibility ; {A}cceptability ; {M}ixed methods ; {C}luster randomized trial ; {C}omplex intervention ; {CAMEROUN} ; {OUGANDA}},
  booktitle = {},
  journal = {{P}ilot and {F}easibility {S}tudies},
  volume = {8},
  numero = {1},
  pages = {39 [12 ]},
  year = {2022},
  DOI = {10.1186/s40814-022-00996-3},
  URL = {https://www.documentation.ird.fr/hor/fdi:010084328},
}