Reyne B. auteur aut IRD Selinger Christian auteur aut IRD Sofonea M. T. auteur aut IRD Miot S. auteur aut IRD Pisoni A. auteur aut IRD Tuaillon E. auteur aut IRD Bousquet J. auteur aut IRD Blain H. auteur aut IRD Alizon S. auteur aut IRD text journalArticle eng text/pdf reformatted digital access Background: The COVID-19 epidemic has spread rapidly within aged-care facilities (ACFs), where the infection-fatality ratio is high. It is therefore urgent to evaluate the efficiency of infection prevention and control (IPC) measures in reducing SARS-CoV-2 transmission. Methods: We analysed the COVID-19 outbreaks that took place between March and May 2020 in 12 ACFs using reverse transcription-polymerase chain reaction (RT-PCR) and serological tests for SARS-CoV-2 infection. Using maximum-likelihood approaches and generalized linear mixed models, we analysed the proportion of infected residents in ACFs and identified covariates associated with the proportion of infected residents. Results: The secondary-attack risk was estimated at 4.1%, suggesting a high efficiency of the IPC measures implemented in the region. Mask wearing and the establishment of COVID-19 zones for infected residents were the two main covariates associated with lower secondary-attack risks. Conclusions: Wearing masks and isolating potentially infected residents appear to be associated with a more limited spread of SARS-CoV-2 in ACFs. specialized COVID-19 aged-care facilities mask wearing generalized linear mixed models secondary-attack risk FRANCE 050 052 020 50 6 1788-1794 2021 0300-5771 https://www.documentation.ird.fr/hor/fdi:010084235 10.1093/ije/dyab121 0300-5771 [F B010084235] https://www.documentation.ird.fr/hor/fdi:010084235 https://horizon.documentation.ird.fr/exl-doc/pleins_textes/2022-03/010084235.pdf IRD - Base Horizon / Pleins textes 2022-03-09 2025-02-24 fdi:010084235 fre