@article{fdi:010084201,
  title = {{B}iodiversity and vector-borne diseases : host dilution and vector amplification occur simultaneously for {A}mazonian leishmaniases},
  author = {{K}ocher, {A}. and {C}ornuault, {J}. and {G}antier, {J}. {C}. and {M}anzi, {S}. and {C}havy, {A}. and {G}irod, {R}. and {D}usfour, {I}. and {F}orget, {P}. {M}. and {G}inouves, {M}. and {P}revot, {G}. and {G}u{\'e}gan, {J}ean-{F}ran{\c{c}}ois and {B}anuls, {A}nne-{L}aure and {T}hoisy, {B}. and {M}urienne, {J}.},
  editor = {},
  language = {{ENG}},
  abstract = {{C}hanges in biodiversity may impact infectious disease transmission through multiple mechanisms. {W}e explored the impact of biodiversity changes on the transmission of {A}mazonian leishmaniases, a group of wild zoonoses transmitted by phlebotomine sand flies ({P}sychodidae), which represent an important health burden in a region where biodiversity is both rich and threatened. {U}sing molecular analyses of sand fly pools and blood-fed dipterans, we characterized the disease system in forest sites in {F}rench {G}uiana undergoing different levels of human-induced disturbance. {W}e show that the prevalence of {L}eishmania parasites in sand flies correlates positively with the relative abundance of mammal species known as {L}eishmania reservoirs. {I}n addition, {L}eishmania reservoirs tend to dominate in less diverse mammal communities, in accordance with the dilution effect hypothesis. {T}his results in a negative relationship between {L}eishmania prevalence and mammal diversity. {O}n the other hand, higher mammal diversity is associated with higher sand fly density, possibly because more diverse mammal communities harbor higher biomass and more abundant feeding resources for sand flies, although more research is needed to identify the factors that shape sand fly communities. {A}s a consequence of these antagonistic effects, decreased mammal diversity comes with an increase of parasite prevalence in sand flies, but has no detectable impact on the density of infected sand flies. {T}hese results represent additional evidence that biodiversity changes may simultaneously dilute and amplify vector-borne disease transmission through different mechanisms that need to be better understood before drawing generalities on the biodiversity-disease relationship.},
  keywords = {amplification effect ; {C}ulicidae ; dilution effect ; i{DNA} ; metabarcoding ; phlebotomine sand fly ; zoonotic disease ; {GUYANE} {FRANCAISE} ; {AMAZONIE}},
  booktitle = {},
  journal = {{M}olecular {E}cology},
  volume = {[{E}arly access]},
  numero = {},
  pages = {[15 p.]},
  ISSN = {0962-1083},
  year = {2022},
  DOI = {10.1111/mec.16341},
  URL = {https://www.documentation.ird.fr/hor/fdi:010084201},
}