Brugere-Picoux J. auteur aut IRD Leroy Eric auteur aut IRD Angot J. L. auteur aut IRD Rosolen S. G. auteur aut IRD text journalArticle fre text/pdf reformatted digital access The concept of "one health" applies perfectly to human health and animal health because many diseases are zoonoses. There are many historical examples of effective collaboration between veterinary medicine and human medicine in the development of the first vaccines used in the world (smallpox, rabies, tetanus, diphtheria, tuberculosis, etc.). But when a new disease appears in animals, the risk of possible transmission to humans is difficult to estimate. In the tatter case, the toss of consumer confidence in the face of scientific uncertainties can cause a health crisis (examples of bovine spongiform encephatopathy and H5N1 avian plague). But the most serious crisis that we have known since early 2020 is Covid-19 pandemic, which confirms that the modification of the ecosystems of certain wild species such as the horseshoe bats can have significant consequences for the public health. Animals infected with Covid-19 have been contaminated by humans but we cannot currently exclude an animal reservoir risk for SARS-CoV-2 which has circulated around the world. specialized One health Vaccinology Bovine spongiform encephalopathy Avian plague Covid-19 Zoonoses 050 080 052 021 206 1 138-145 2022 0001-4079 https://www.documentation.ird.fr/hor/fdi:010083913 10.1016/j.banm.2021.11.008 0001-4079 [F B010083913] https://www.documentation.ird.fr/hor/fdi:010083913 https://horizon.documentation.ird.fr/exl-doc/pleins_textes/2022-02/010083913.pdf IRD - Base Horizon / Pleins textes 2022-02-04 2022-02-06 fdi:010083913 fre